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Not yet recruiting NCT06940726

Exploring the Links Between Hearing, Cognition and Brain Activity in People With Tinnitus

No phase Interventional Tinnitus

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Quality of Life questionnaires, Hearing tests, Auditory prediction task, Attention task.
Who it may be relevant to
Registry conditions: Tinnitus. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Exploration Des Liens Entre Audition, Cognition et activité cérébrale Chez Des Personnes présentant un acouphène

Overview

The goal of this observational study is to understand the mechanisms underlying tinnitus, and improve the clinical assessment strategies needed to develop targeted therapeutic interventions by comparing endogenous attention capacities in healthy subjects and subjects with tinnitus

Interventions

  • Other Quality of Life questionnaires
    Subjects will complete a number of self-questionnaires on subjects such as attention span, anxiety levels and sleep quality.
  • Other Hearing tests
    listening to sounds on headphones and repeating words
  • Behavioral Auditory prediction task
    listening to sounds and assessing auditory perception
  • Behavioral Attention task
    assessment of reaction time to visual or auditory cues

Primary outcome measures

  • Contingent negative variation (CNV) in EEG [Time frame: 2 hours]
Secondary outcome measures (6)
  • Response reaction time (in ms) [Time frame: 2 hours]
  • Answer accuracy (% correct answers) [Time frame: 2 hours]
  • Cerebral oscillations (alpha bands) obtained by EEG during behavioural tasks [Time frame: 2 hours]
  • Skin conductance (μS) [Time frame: 2 hours]
  • Heart rate variability (in ms) [Time frame: 2 hours]
  • Pupillometry (pupillary dilation in mm) [Time frame: 2 hours]

Eligibility criteria

Inclusion criteria

  • Age ≥ 18 years
  • Good written and oral comprehension of the French language
  • Normal or corrected vision

Group of people with tinnitus :

\- Chronic tinnitus > 3 months, uni or bilateral, stable (no period of remission)

Control group :

\- No tinnitus

Exclusion criteria

  • Presence of a known neurological disorder
  • Presence of a known degenerative pathology
  • Presence of a known hearing impairment
  • Presence of a motor disability of the upper limbs
  • Severe or profound deafness on one or both sides
  • Person under legal protection (guardianship, curatorship, etc.)
  • Use of hearing aids

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Basic science

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT06940726 · 2024-159 · 2025-A00267-42

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗