Efficacy and Safety of Pulsed Radiofrequency Combined With Platelet Rich Plasma to Treat Idiopathic Glossopharyngeal Neuralgia (GPN)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Glossopharyngeal Neuralgia, Pulsed Radiofrequency, Platelet Rich Plasma. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Efficacy and Safety of the Application of Pulsed Radiofrequency, Combined With Platelet Rich Plasma, to the Treatment of Idiopathic Glossopharyngeal Neuralgia (GPN): A Study Protocol for a Multi-Center, Prospective, Open-Label, Propensity Score Match Cohort Study
Overview
To investigate the efficacy and safety of the application of PRF combined PRP to the for the treatment of GPN.
Primary outcome measures
- Numeric rating scale (NRS) score [Time frame: 1day, 3days, 1week, 2weeks, 1month, 3months, 6months, and 1year following the procedure]
Secondary outcome measures (1)
- Barrow Neurological Institute pain scale(BNI score) [Time frame: 1day, 3days, 1week, 2weeks, 1month, 3months, 6months, and 1year following the procedure]
Eligibility criteria
Inclusion criteria
- age >18 years;
- diagnosed with idiopathic GPN according to the third International Classification of Headache Disorders (ICHD) classification;
- patients who failed pharmacotherapy or intolerable side effects of medication;
- undergoing PRF for GPN;
- at least 1 month of follow-up recordings.
Exclusion criteria
- Patients with bilateral GPN;
- Abnormalities in blood measurements, liver and kidney function, blood glucose, coagulation, electrocardiography or chest radiography;
- Infection at the puncture site;
- Previous mental illness;
- Previous history of narcotic drug abuse;
- Prior anticoagulant or antiplatelet therapy;
- An implantable pulse generator;
- Current pregnancy or breast feeding.
- Patients with incomplete medical records (lack of baseline data or postoperative follow-up data).
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Beijing Tiantan Hospital — Beijing
Identifiers
NCT: NCT06931457 · KY 2023-263-03-07