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Recruiting NCT06928727

Ocular Characteristics in Patients With Craniosynostosis

Observational Craniosynostosis Strabismus Intracranial Hypertension Amblyopia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Craniosynostosis, Strabismus, Intracranial Hypertension, Amblyopia. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

Craniosynostosis are cranial deformations due to the premature closure of one or more cranial sutures. These deformations affect approximately one in 2.500 births. In most cases, craniosynostoses are isolated with unknown (non syndrome). On the other hand, 20% of these deformations are associated with other concentration (syndrome). Craniosynostosis has morphological (associated dysmorphism) and functional (growth conflict between the skull and the brain) repercussions. Ophthalmological disorders are frequent: refractive disorders, oculomotor disorders, optic nerve damage, sensory damage. This retrospective study aims to describe the ocular clinical characteristics associated with craniosynostosis in patients followed at the Amiens University Hospital.

Primary outcome measures

  • Rate of strabismus and amblyopia [Time frame: 6 months]
Secondary outcome measures (1)
  • Rate of intracranial hypertension [Time frame: 6 months]

Eligibility criteria

Inclusion criteria

  • Diagnosis of craniostenosis

Exclusion criteria

  • Posterior plagiocephalia

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-only

Study locations

France · 1 center
  • CHRU Amiens — Amiens

Identifiers

NCT: NCT06928727 · PI2025_843_0075

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗