7.0T Magnetic Resonance Imaging Study for Hepatic Encephalopathy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: 7.0T MRI-Scan.
- Who it may be relevant to
- Registry conditions: Hepatic Encephalopathy (HE), MRI, fMRI Research. Basic parameters: 18 years — 89 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This clinical trial study aims to detect the imaging characteristics of patients with hepatic encephalopathy (HE) using 7-Tesla (7T) magnetic resonance imaging (MRI).
Detailed description
In this study, we analyzed the imaging characteristics of HE. First, with the advantages of 7TMRI, we analyzed the differences in imaging characteristics between HE patients and the healthy, including brain functional imaging and structural imaging. Second, we analyzed the differences in imaging characteristics between different subgroups of HE patients. Finally, we analyzed the correlation between the prognostic results of HE patients after follow-up and the imaging characteristics.
Interventions
- Other 7.0T MRI-Scan
7.0T MRI-Scan
Primary outcome measures
- Functional connectivity and structural alterations between individuals with different subtypes of HE and healthy subjects. [Time frame: 5 years]
Secondary outcome measures (1)
- Correlation between spectral features of clinical variables and spectral features of imaging. [Time frame: 5 years]
Eligibility criteria
Inclusion criteria
- Patients with clinical suspected or diagnosed hepatic encephalopathy according to relevant guidelines.The patient's education level is above primary school level.
- Regular follow-up.
Exclusion criteria
- Contraindications to MRI.
- Patients with cerebrovascular disease, brain tumors, epilepsy, other neurodegenerative disease.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
China · 1 center
- Chinese PLA General Hospital — Beijing
Identifiers
NCT: NCT06923254 · Hepatic encephalopathy-301