Real-Time (TRUS) Guidance in Endoscopic Treatment of BPH
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: TRUS-Guided TURP and enucleation, Standard TURP and enucleation.
- Who it may be relevant to
- Registry conditions: BPH (Benign Prostatic Hyperplasia). Basic parameters: 50 years — 80 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Standard Versus Transrectal Ultrasound (TRUS)-Guided Endoscopic Treatment of Benign Prostatic Hyperplasia: A Prospective Randomized Controlled Trial
Overview
The study aims to evaluate the role of TRUS in improving the efficacy and safety of endoscopic enucleation of prostate and TURP.
Detailed description
Standard TURP is an established procedure for managing BPH but has limitations, including the risk of incomplete adenoma removal and complications such as bleeding. Research on transurethral enucleation techniques has demonstrated potential for improved outcomes, especially in larger prostates. However, challenges persist in achieving precise resection boundaries and minimizing intraoperative risks.
TRUS, widely utilized for prostate biopsy and volume assessment, has recently gained attention for its intraoperative applications. Studies show that real-time TRUS provides accurate imaging of prostate anatomy and resection planes, helping surgeons better differentiate adenomatous tissue from surrounding structures. This enhances surgical precision, reduces intraoperative bleeding, and minimizes residual tissue, leading to better outcomes in procedures like TURP and enucleation.
Current TURP and enucleation approaches depend heavily on endoscopic visual guidance, which, despite significant advancements, can lead to residual tissue, excessive bleeding, and prolonged recovery. While enucleation techniques have addressed some of these challenges, they remain less accessible due to high costs and steep learning curves, making them unsuitable for all healthcare settings.
Integrating TRUS into TURP or enucleation offers the potential to address these limitations by enhancing tissue differentiation and guiding precise resection. This study aims to evaluate the efficacy of TRUS in reducing complications, achieving complete tissue removal, and improving patient recovery outcomes, potentially paving the way for its routine adoption in BPH surgery.
Interventions
- Procedure TRUS-Guided TURP and enucleation
realtime TRUS guidance during the procedure (TURP and enucleation) - Procedure Standard TURP and enucleation
No TRUS guidance during the procedure (TURP and enucleation)
Primary outcome measures
- efficacy of endoscopic treatment of BPH [Time frame: At 12 weeks after the procedure]
Eligibility criteria
Inclusion criteria
- Male patients aged 50-80 years
- Diagnosed with benign prostatic hyperplasia (BPH) and scheduled for TURP or prostatic adenoma enucleation.
- The patients have clear indication for endoscopic surgery (according to the guidelines).
- Clinically fit patients for surgery.
- Signed an informed consent.
Exclusion criteria
- • Prostate cancer
- Previous urethral or prostate surgery
- Neurogenic bladder
- Urethral stricture
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Assiut university — Asyut
Identifiers
NCT: NCT06922968 · TRUS with TURP and enucleation