HIPEC Surgery and Hemodynamics
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Hemodynamics, Cytoreductive Surgery, Hyperthermic Intraperitoneal Chemotherapy (HIPEC). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Perioperative Hemodynamic and Respiratory Changes During Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Combined With Cytoreductive Surgery
Overview
Hyperthermic Intraperitoneal Chemotherapy (HIPEC) involves the intraoperative administration of heated chemotherapeutic agents into the abdominal cavity following cytoreductive surgery (CRS). The increasing use of CRS combined with HIPEC has introduced certain procedural and physiological considerations that distinguish it from other surgical interventions, posing unique challenges for researchers and clinicians alike. Despite advancements in surgical and anesthetic techniques, this combined approach is frequently associated with significant hemodynamic instability, coagulation abnormalities, respiratory complications, and nutritional imbalances. The study aims to contribute to the existing body of knowledge by examining the physiological alterations induced by HIPEC, thereby offering practical insights and guidance for investigators involved in the management and study of this complex therapeutic modality.
Primary outcome measures
- physiological parameter ; heart rate [Time frame: Intraoperatively]
- physiological parameter; systolic/diastolic blood pressure [Time frame: Intraoperatively]
- physiological parameter; SpO2 [Time frame: Intraoperatively]
- anesthesia device measurement parameter; EtCo2 [Time frame: Intraoperatively]
- anesthesia device measurement parameter; Pmax [Time frame: Intraoperatively]
Secondary outcome measures (2)
- Preoperative data [Time frame: 24 hours before surgery]
- Postoperative data [Time frame: 24 hours after surgery]
Eligibility criteria
Inclusion criteria
- ≥18 years old Patients planned to undergo cytoreductive surgery with hyperthermic intraperitoneal chemotherapy
- ASA II-III-IV physical class
Exclusion criteria
- <18 years
- Emergency cases
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 1 center
- Ankara Etlik City Hospital — Ankara
Identifiers
NCT: NCT06922227 · 530