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Recruiting NCT06917365

Clinical Performance of XPEO-E Liner in SERF Dual-mobility Cups

Observational Total Hip Arthroplasty (THA)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Total Hip Arthroplasty (THA). Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

XPEO-E liner is CE marked under MDD 93/42/CEE by equivalency with CI E liner. No pertaining data on XPEO-E liner is yet available. However, clinical evaluation concludes on a reaching of performance and safety and compliance with essential requirements. This study intends to collect data on XPEO-E in order to allow a transit to MDR 2017/745 (EU). XPEO-E liner is intended to be used with NOVAE cups and SERF femoral heads and Stems. XPEO-E liner will be used according to their CE marking. These devices are intended for hip replacements with the aim of improving quality of life and reducing pain by replacing a damaged joint. The follow-up visits are established according to the current practice. Additional procedure will only consist on questionnaires that will be filled by the patient and/or the surgeons.

Primary outcome measures

  • Functional improvement [Time frame: Per operative period to 5 years]
Secondary outcome measures (7)
  • Survival rate [Time frame: Per operative period to 5 years]
  • Functional improvement [Time frame: Per operative period to 5 years]
  • Functional improvement [Time frame: Per operative period to 5 years]
  • Pain release [Time frame: Pre operative period to 5 years]
  • Patient's quality of life [Time frame: Pre operative period to 5 years]
  • Patient's satisfaction [Time frame: Post operative period to 5 years]
  • Adverse events [Time frame: Per operative period to 5 years]

Eligibility criteria

Inclusion criteria

  • Male or female adults.
  • Patient that needs to be implanted with a SERF total hip prosthesis.
  • Patient responding to IFU requirement.
  • Patient affiliated to French social security.
  • Patient who has provided a dated and signed informed consent form.

Exclusion criteria

  • Patient protected by a French legal measure (under legal protection, guardianship or curatorship).
  • Patient unable of expressing consent, according to the investigator.
  • Patient deprived of liberty or hospitalized against his consent.
  • Pregnant or breastfeeding patient.
  • Patient presenting a contraindication to the implantation of medical devices according to the instructions for use.
  • Patient with a contraindication to radiographic follow-up.
  • Patient not being, a priori, capable of respecting the schedule of follow-up visits, according to the investigator.
  • Patient unable to complete a self-questionnaire, according to the investigator.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

France · 5 centers
  • CHU Dijon — Dijon
  • HCL Croix-Rousse — Lyon
  • HCL Lyon Sud — Lyon
  • CHU Saint Etienne — Saint-Etienne
  • CHU Strasbourg — Strasbourg

Identifiers

NCT: NCT06917365 · 2024-A02261-46

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗