Evaluation of the Efficacy of Dissociation-Focused Cognitive Behavior Therapy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: CBT-CD psychotherapy.
- Who it may be relevant to
- Registry conditions: Dissociative Disorder. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Evaluation of the Efficacy of Dissociation-Focused Cognitive Behavior Therapy: a Multicenter Randomized Controlled Trial
Overview
Dissociative symptoms and disorders are particularly prevalent in the general population and among people suffering from psychiatric disorders. To date, no treatment has proven effective for this type of problem. Exploratory studies (without control group) have been carried out. Among these studies, dissociation-focused cognitive behavioral therapy (DF-CBT) seems promising. DF-CBT is based on a solid empirical model that has received numerous scientific evidence.
Interventions
- Other CBT-CD psychotherapy
9 weekly sessions of CBT-CD psychotherapy
Primary outcome measures
- Difference in Dissociative Experience Scale (DES) [Time frame: Between randomization and 3 months after]
Secondary outcome measures (6)
- Hetero-administered visual analogue scale [Time frame: At randomization, 3 months and 6 months after]
- Dissociation Questionnaire (DIS-Q) [Time frame: At randomisation, 3 months and 6 months after]
- Hospital Anxiety Depression Scale (HADS) [Time frame: Randomization, 3 months and 6 months after]
- Post traumatic stress disorder checklist scale (PCL-5) [Time frame: Randomization, 3 months and 6 months after]
- Satisfaction With Life Scale (SWLS) [Time frame: Randomization, 3 months and 6 months after]
- Dissociative Experiences Scale (DES) [Time frame: At 6 months after randomization]
Eligibility criteria
Inclusion criteria
- ≥ 18 years
- Membership of a social security scheme
- Participant's express consent
- Have at least one diagnosis of dissociative disorder among the following:
depersonalization/derealization disorder, dissociative identity disorder, unspecified dissociative disorder.
- Be able to carry out psychotherapy sessions.
- If taking psychiatric medication, treatment must have been stable for at least 30 days.
Exclusion criteria
- Present one of the following current diagnoses: substance use disorder (excluding tobacco), neurodevelopmental disorder, anorexia nervosa, severe depressive disorder, schizophrenia spectrum disorder, bipolar disorder, personality disorder other than borderline personality disorder.
- Present cognitive deficits.
- Be engaged in psychotherapeutic work.
- Be undergoing benzodiazepine treatment.
- Pregnant women and breastfeeding women
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
France · 8 centers
- Psychiatrie / CHU ANGERS — Angers
- Centre régional du Psychotraumatisme des Hauts de France / CHU LILLE — Lille
- Urgences psychiatrique / CHU MONTPELLIER — Montpellier
- Unité de neuromodulation en psychiatrie / CHU NANTES — Nantes
- Centre départemental de Psychotraumatologie (unité TCC) / ORLEANS — Orléans
- Centre Régional du Psychotraumatisme du Grand Est / CHU STRASBOURG — Strasbourg
- Centre Régional du Psychotraumatisme CRP / CHRU TOURS — Tours
- Unité de Neuromodulation / CHU de Tours — Tours
Identifiers
NCT: NCT06917209 · DR240330