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Recruiting NCT06914349

Antecolic Versus Retrocolic Gastrojejunostomy During Whipple's Procedure

No phase Interventional Pancreatic Cancer Resectable Pancreas Neoplasms

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Antecolic gastrojejunostomy, Retrocolic gastrojejunostomy.
Who it may be relevant to
Registry conditions: Pancreatic Cancer Resectable, Pancreas Neoplasms. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Greece
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Antecolic Versus Retrocolic Gastrojejunostomy Following Pancreaticoduodenectomy: a Prospective Randomised Study

Overview

Aim: This randomized clinical study aims to compare occurrence of DGE in patients undergoing either antecolic or retrocolic gastrojejunostomy following pancreaticoduodenectomy. Methods: Participants of this study will be patients undergoing pylorus preserving pancreaticoduodenectomy at the Surgical Department of the University Hospital of Larissa. Patients will be randomized to undergo either an antecolic or a retrocolic gastrojejunostomy and the occurrence of DGE will then be compared between the two groups. Individuals younger than 18 or older than 75 years old, as well as patients who do not consent to participate in this trial, will be excluded. Expected results: Based on available literature, antecolic gastrojejunostomy may be related with a lower incidence of DGE, without a statistically significant difference between the two methods. We aim to show if one of the two methods of gastrointestinal reconstruction (antecolic versus retrocolic) affects DGE.

Interventions

  • Procedure Antecolic gastrojejunostomy
    Gastrojejunostomy in front of the transverse colon
  • Procedure Retrocolic gastrojejunostomy
    Gastrojejunostomy through the transverse mesocolon

Primary outcome measures

  • Delayed Gastric Emptying [Time frame: 3 years]

Eligibility criteria

Inclusion criteria

  • Age over 18 years old
  • Elective pancreaticoduodenectomy
  • Signed consent form

Exclusion criteria

  • Age under 18 years old
  • Patients who are participants in other trials that may affect the results of this study
  • Patients who do not consent to participate in the study

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Single group
Masking
Double blind
Primary purpose
Treatment

Study locations

Greece · 1 center
  • University of Thessaly — Larissa

Identifiers

NCT: NCT06914349 · University hospital of Larissa

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗