Preoperative TAP Block Versus Postoperative TAP Block in Patients Undergoing Laparoscopic Cholecystectomy: a Randomized Controlled Trial
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Preoperative TAP Block, Postoperative TAP block.
- Who it may be relevant to
- Registry conditions: TAP Block. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The goal of this clinical trial is to learn if the regional anesthesia technique "TAP block" provide more analgesia when performed before or after the surgery. The main questions it aims to answer are: Does preoperative TAP block provide greater analgesia than postoperative TAP block? Patients receiving preoperative TAP block will have less pain and take less painkillers than patients receiving postoperative TAP block? Participants will: Receive preoperative or postoperative TAP block They will be asked about their pain levels during the hospital stay.
Detailed description
The TAP block is a safe, easy-to-perform, and effective technique for managing postoperative pain. It reduces opioid consumption and increases patient satisfaction. Despite recent studies indicating that postoperative TAP block might be more effective than preoperative TAP block in reducing opioid use within 24 hours, the optimal timing of its administration (before or after surgery) remains unclear.
In this study we will compare preoperative to postoperative TAP block in patients undergoing laparoscopic cholecistectomy.
The primary aim of this study is to determine the difference in postoperative pain control between preoperative and postoperative TAP block administration in patients undergoing laparoscopic cholecystectomy.
The primary objective will be to evaluate the difference in postoperative pain at rest, 24 hours after surgery, between patients receiving preoperative versus postoperative TAP block. Pain will be assessed using the Numeric Rating Scale (NRS) from 0 to 10.
Secondary objectives will be intraoperative and postoperative opioids, postoperative nausea and vomiting, pain at resnt and on movement at 0,6,12,24 hours.
Interventions
- Procedure Preoperative TAP Block
Patients will receive preoperative TAP block - Procedure Postoperative TAP block
Patients will receive postoperative TAP block
Primary outcome measures
- Patient reported pain on movement at 24 hours after the surgery [Time frame: At the 24th hour after the end of the surgery.]
Secondary outcome measures (10)
- Patient reported pain on movement (cough) at the end of the surgery [Time frame: At the end of the surgery.]
- Patient reported pain on rest at the end of the surgery [Time frame: At the end of the surgery.]
- Patient reported pain on rest at 6 hours after the surgery [Time frame: At the 6th hour after the end of the surgery.]
- Patient reported pain on movement at 6 hours after the surgery [Time frame: At the 6th hour after the end of the surgery.]
- Patient reported pain on rest at 12 hours after the surgery [Time frame: At the 12th hour after the end of the surgery.]
- Patient reported pain on movement at 12 hours after the surgery [Time frame: At the 12th hour after the end of the surgery.]
- Patient reported pain on rest at 24 hours after the surgery [Time frame: At the 24th hour after the end of the surgery.]
- Difference in intraoperative opioids [Time frame: From the enrollment to the extubation]
- Difference in postoperative opioids [Time frame: From the extubation to the 24th postoperative hours]
- Number of participants experiencing postoperative nausea and vomiting [Time frame: From extubation to the 24th postoperative hour]
Eligibility criteria
Inclusion criteria
- ASA I-II patients
- Age >18 years
- Informed consent
Exclusion criteria
- History of chronic pain
- Beta-blocker therapy
- Allergy to the drugs used in the study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Italy · 1 center
- University Hospital of Padua — Padua
Identifiers
NCT: NCT06903182 · 6126/AO/24