Multimodal Monitoring Study in Neuro Critical Care
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Study the evolution and correlation between cerebral autoregulation index.
- Who it may be relevant to
- Registry conditions: Subarachnoidal Hemorrhage, Intacranial Hypertension, Acute Trauma Brain Injury. Basic parameters: 18 years — 90 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
During the first week after an acute cerebral injury, neurologic clinical exam is often irrelevant, limited by sedation use or spontaneous consciousness disorders. Hence, neurological monitoring of brain oxygen consumption, metabolic disorders, electrical activity is used to follow and prevent delayed cerebral injuries. Among those instruments, numerous are often described: intra cranial pressure monitoring, brain tissue oxygen pressure monitoring, scalp electroencephalography, continuous electroencephalography and Near infrared Red Spectroscopy (NIRS). Even if the value of some of those technologies are well known, many remain part of a research domain. Here we will not only try to study the correlation between different cerebral autoregulation's index described in the scientific literature but also will we try to identify and describe EEG and cardiorespiratory changes during the first week following brain injury. The objective of this study is to investigate the pathophysiology of acute brain injury and explore potent biomarkers of multimodal monitoring during the first week following acute brain injury.
Interventions
- Other Study the evolution and correlation between cerebral autoregulation index
Objective n°1: Study the correlation between autoregulation index: The investigators will look for a correlation between several auroregulation index such as the PRx, ORx and Cox. Objective n°2: Evaluation and detection of EEG prognostic patterns: The investigators will look for quantitaive EEG changes during the early phase of acute brain injuries.
Primary outcome measures
- Correlation between ORx and PRx [Time frame: Multimodal neuro monitoring is used from 1 to 15 days after the acute brain injury.]
Eligibility criteria
Inclusion criteria
- \- Patients hospitalized in neurologic critical care in Wertheimer Hospital, Bron
- Monitored with the CNS MOBERG® monitoring system
Exclusion criteria
- \- Refusal to participate
- Patients under legal protection
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- Hopital Pierre Wertheimer — France
Identifiers
NCT: NCT06900101 · 713