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Recruiting NCT06899867

Comparing Montiroing Cardiac Index by Transpulmonary Thermodilution and Transesophageal Echocardiography During Liver Transplantation

Observational Liver Transplantation

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Measure of cardiac index with thermodilution and transesophageal echocardiography, Surgical anastomosis echography.
Who it may be relevant to
Registry conditions: Liver Transplantation. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Is Cardiac Index, Assessed by Transpulmonary Thermodilution, Reliable During Liver Transplantation Compared to Transesophageal Echocardiography : a Monocentric Cohort

Overview

Liver transplantation poses challenges due to hemodynamic changes throughout different surgical phases. Monitoring devices are essential for therapeutic adjustments. Transpulmonary thermodilution and transesophageal echocardiography are commonly used, but thermodilution may have limitations depending on the surgery. This study aims to compare cardiac index variations between thermodilution and transesophageal echocardiography during liver transplantation. Patients undergo monitoring with both techniques. Measurements are recorded and reported at multiple time points.

Interventions

  • Other Measure of cardiac index with thermodilution and transesophageal echocardiography
    At 4 times of surgery, end-expiratory occlusion (EEO) test and measure of cardiac index before and after test with ETO and thermodilution
  • Other Surgical anastomosis echography
    Visualisation of surgical anastomosis through transesophageal echocardiography : stenosis, doppler velocity, collar diameter

Primary outcome measures

  • Cardiac index variation measured by thermodilution compared with transesophageal echography [Time frame: At 4 times of surgery: after starting anesthesia, anhepatic phase, reperfusion and surgical anastomosis of biliary ducts. Data reported : - Cardiac Index before and after end-expiratory test. - Transoesophageal echography measurement of cardiac function]

Eligibility criteria

Inclusion criteria

  • liver transplantation
  • adults

Exclusion criteria

  • \- Oesophageal varice ligation < 14 days
  • Mediastinal radiotherapy
  • Femoral bypass
  • Severe lower extremity artery disease

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

France · 1 center
  • Croix Rousse Hsopital — France

Identifiers

NCT: NCT06899867 · 24-5431

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗