Spinal and Supraspinal Control in Chronic Ankle Instability
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: The structured balance training protocol.
- Who it may be relevant to
- Registry conditions: Ankle Injuries, Ankle Sprains. Basic parameters: 18 years — 25 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Cross-Education Effect of Structured Balance Training Program on Spinal and Supraspinal Control in Athletes With Chronic Ankle Instability
Overview
Ankle sprains are common sports injuries that often lead to chronic ankle instability (CAI). Patients with CAI experience deficits in neuromuscular control (NMC), including proprioception and strength. It is believed that damage to the ankle's ligament mechanoreceptors and the peroneal nerve after the initial ankle sprain can cause alterations in NMC, resulting in postural control and dynamic joint stability dysfunction. Inflammation related to recurrent ankle sprains may also contribute to neuromuscular impairments. Evidence suggests that bilateral postural control deficits occur after an ankle sprain, suggesting alterations in the central nervous system (CNS). Rehabilitation for CAI has been shown to lead to bilateral improvements in NMC, potentially due to neural alterations at both the spinal and supraspinal levels. Cross-education, which refers to the muscular crossed effect of unilateral training, has also been proposed as a mechanism for improving contralateral strength in neurologically healthy individuals. While the exact mechanisms underlying cross-education are not yet fully understood, evidence suggests that it involves neural adaptations at both spinal and supraspinal levels. This study aims to investigate the cross-education effect of a 6-week, unilateral balance training on corticomotor excitability, motor neuron pool excitability, and static and dynamic balance in athletes with chronic ankle instability.
Interventions
- Other The structured balance training protocol
The structured balance training protocol consists of 7 exercises including balance and hop stabilization exercises for athletes with chronic ankle instability.
Primary outcome measures
- Proprioceptive-Stabilometric Assessment [Time frame: at the baseline and end of the intervention, 8 weeks]
- Transcranial Magnetic Stimulation [Time frame: at the baseline and end of the intervention, 8 weeks]
- Hoffman Reflex [Time frame: at the baseline and end of the intervention, 8 weeks]
Secondary outcome measures (2)
- Cumberland Ankle Instability Tool [Time frame: at the baseline and end of the intervention, 8 weeks]
- Foot and Ankle Ability Measure (FAAM) [Time frame: at the baseline and end of the intervention, 8 weeks]
Eligibility criteria
Inclusion criteria
- Volunteering to participate in the study,
- Being an athlete between the ages of 18-25,
- Being a player in a field team sport such as basketball, volleyball, and handball,
- Having a history of at least 2 significant grade II LAS diagnosed by a physician,
- Related inflammatory symptoms, "giving away" sensation, obtaining a score ≤25 from the Cumberland Ankle Instability Tool (CAIT),
- A score <90% for the activities of daily living subscale and <80% for the sport subscale from the Foot and Ankle Ability Measure,
- Recurrent episodes of LAS of the injured ankle which occurred within at least 12 months.
Exclusion criteria
- Acute injury of lower extremity musculoskeletal structures in the last three months,
- Orthopedic surgery in any of the lower extremities,
- Bilateral ankle instability,
- Vestibular or balance disorder
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Turkey (Türkiye) · 2 centers
- Yeditepe University Koşuyolu Hospital — Istanbul
- Yeditepe University — Istanbul
Identifiers
NCT: NCT06898554 · YeditepeU23