Epidemiology of Gonococcal Arthritis (EpGAr)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Gonococcal (GC) Infection, Arthritis, Infectious. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Epidemiology of Gonococcal Arthritis
Overview
The aim of this retrospective observational study was to describe the epidemiology of Neisseria gonorrhoeae septic arthritis over the last 10 years at Brest and Rennes university hospitals. The main question is whether there are any risk factors based on the epidemiological and clinical data on these cases. The second objective is to characterize the gonococcal strains isolated in order to determine whether there is a common clone, a virulence factor or specific resistance genes.
Primary outcome measures
- Age [Time frame: 10 years]
- Date of sampling [Time frame: 10 years]
- Type of sample [Time frame: 10 years]
- Rate of white blood cells [Time frame: 10 years]
- Sexually transmitted infection [Time frame: 10 years]
- Men who have sex with men [Time frame: 10 years]
- HIV pre-exposure prophylaxis (PreP) [Time frame: 10 years]
- Comorbidities [Time frame: 10 years]
- Imaging [Time frame: 10 years]
- Blood cultures (peripheral blood) [Time frame: 10 years]
Secondary outcome measures (3)
- Molecular typing: clone [Time frame: 10 years]
- Molecular typing: virulence factors [Time frame: 10 years]
- Molecular typing: resistance genes [Time frame: 10 years]
Eligibility criteria
Inclusion criteria
- Patients with a Neisseria gonorrhoeae-positive joint sample (from an enrichment vial or a native sample) between 2014 and 2024.
Exclusion criteria
- Patients with Neisseria gonorrhoeae-negative joint sample (from enrichment vial or native sample).
- Patients who have expressed opposition to inclusion in the study.
- Patients under legal protection (guardianship, curatorship, etc.).
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 2 centers
- Rennes University Hospital — Rennes
- CHU de BREST — Brest
Identifiers
NCT: NCT06897943 · 29BRC24.0339 - EpGAr