Comparison of Preoperative Frailty Assessment Tools
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Assessment of frailty using multiple tools.
- Who it may be relevant to
- Registry conditions: Frailty, Frailty in Older Adults, Frailty/Sarcopenia. Basic parameters: from 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Germany
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Evaluation of a Feasible Frailty Assessment Tool for Preoperative Risk Evaluation of Older Patients
Overview
Frailty is a significant risk factor for postoperative complications and functional decline. Preoperative assessment of frailty is therefore recommended in all older adults. However, despite the availability of many frailty tools, few have been tested in the preoperative setting and there is little comparison of their predictive value in identifying patients at risk. The aim of this study is to investigate which of the following instruments for determining frailty has the highest predictive power with regard to the occurrence of postoperative complications: Risk Analysis Index, Clinical Frailty Scale, the Groningen Frailty Indicator, the Edmonton Frail Scale and the LUCAS-FI. The aim of this research project is to identify a suitable frailty instrument for preoperative risk stratification of older patients during the premedication visit.
Interventions
- Other Assessment of frailty using multiple tools
This is an observational study without any intervention. Frailty is assessed using multiple tools and postoperative outcome is compared.
Primary outcome measures
- Complications in the first 30 days after surgery [Time frame: 30 days]
Secondary outcome measures (12)
- Functional state (activities of daily living) [Time frame: one, three and six months after surgery]
- Postoperative Quality of Recovery [Time frame: postoperative day 2]
- Muscle loss during hospitalisation [Time frame: From date of enrollment, up to 4 weeks after surgery]
- Postoperative delirium [Time frame: postoperative day 1 to 5]
- Length of stay [Time frame: from day of surgery, up to 4 weeks after surgery]
- Discharge destination [Time frame: up to 4 weeks after surgery]
- Cognitive state [Time frame: 3 and 6 months after surgery]
- Quality-of-Life (QoL) [Time frame: 3 and 6 months after surgery]
- Frailty progression measured by LUCAS-FI [Time frame: 3 and 6 months after surgery]
- Frailty progression measured by GFI (questionnaire) [Time frame: 3 and 6 months after surgery]
- Frailty progression measured by EFS [Time frame: 3 and 6 months after surgery]
- Frailty progression by RAI measurement. The Risk Analysis Index (RAI) is evaluated by summing weighted risk factors and protective variables, with higher scores indicating greater patient vulnerability. [Time frame: 3 and 6 months after surgery]
Eligibility criteria
Inclusion criteria
- 70 years and older
- scheduled surgery
- estimated time of surgery 120 Minutes or more
Exclusion criteria
- insufficient German language skills (for cognitive testing)
- mental retardation
- relevant psychiatric disorder (not allowing for cognitive testing)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Germany · 1 center
- University Medical Centre Hamburg — Hamburg
Identifiers
NCT: NCT06889545 · 2024-101410-BO-ff