Recruiting NCT06887894
Biomarkers and Unstable Carotid Plaque
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Carotid endarterectomy.
- Who it may be relevant to
- Registry conditions: Carotid Artery Diseases. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
EVALUATION OF NEW BIOMARKERS IN THE IDENTIFICATION OF UNSTABLE CAROTID PLAQUE
Overview
This prospective study investigated associations between circulating miRNAs and symptomatic and asymptomatic ICAS, carotid plaque morphology and future cardiovascular events.
Interventions
- Procedure Carotid endarterectomy
Carotid endarterectomy, plaque histological analysis and miRNA expression
Primary outcome measures
- miRNA levels [Time frame: 30 days]
Eligibility criteria
Inclusion criteria
- Presence of significant internal carotid artery stenosis referred to carotid artery endarterectomy.
- Age>18 years
Exclusion criteria
- Presence of significant internal carotid artery stenosis referred to carotid artery stenting
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Italy · 1 center
- Fondazione Policlinico Universitario A. Gemelli IRCCS — Roma
Identifiers
NCT: NCT06887894 · 0032543/19