Optical Coherence Tomography in Retinal Vein Occlusion
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Optical Coherence Tomography (OCT). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Optical Coherence Tomography Data As a Prognostic Indicator in Retinal Vein Occlusion
Overview
This study aims to evaluate how optical coherence tomography (OCT) can help predict outcomes in patients with retinal vein occlusion (RVO), a condition that affects blood flow in the retina. RVO can cause macular edema, which is swelling in the part of the eye responsible for central vision. The study will use OCT scans to assess changes in the retina and how these changes relate to vision improvement over time.
Detailed description
Objectives Evaluate how OCT data can predict visual outcomes by analyzing retinal changes and macular edema characteristics.
Assess the correlation between baseline OCT biomarkers and visual acuity improvements over time.
Study Design Type: Cross-sectional study.
Setting: Conducted at several eye care centers in Egypt.
Participants Inclusion Criteria: Adults with branch or central RVO, macular edema confirmed by OCT, and no prior RVO in the affected eye.
Exclusion Criteria: Other retinal diseases, recent intraocular surgery, or significant media opacities.
Procedures Informed Consent and History Taking.
Ophthalmologic Examination: Includes BCVA, IOP, slit-lamp biomicroscopy, and fundus examination.
OCT Imaging: Using NIDEK RS-330 Retina scan duo 2 (SD-OCT) to assess macular changes.
OCT Image Evaluation: Classification of macular edema types and assessment of biomarkers like subretinal fluid and cystoid changes.
Primary outcome measures
- changes in OCT biomarkers and visual acuity post-treatment. [Time frame: 6 months]
Eligibility criteria
Inclusion criteria
- Adults aged 18 years or older.
Patients diagnosed with branch or central retinal vein occlusion.
Patients with macular edema confirmed by OCT due to vein occlusion.
Patients with no prior history of RVO in the affected eye.
Exclusion criteria
- Presence of other retinal diseases that could affect OCT interpretation (e.g., diabetic retinopathy, age-related macular degeneration).
History of intraocular surgery within the last three months.
Presence of significant media opacities (e.g., dense cataract, vitreous hemorrhage) that interfere with OCT imaging.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT06886893 · OCT in retinal vein occlusion