Endoscopic Findings in Patients With Upper GIT Bleeding
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: endoscope.
- Who it may be relevant to
- Registry conditions: GIT - Gastrointestinal Tract Hemorrhage. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Endoscopic Findings in Patients With Upper GIT Bleeding in Assiut University Hospital
Overview
This study aims to identify the causes of upper gastrointestinal bleeding through comprehensive evaluation via upper endoscopy in Assiut University Hospital and contribute valuable insights into effective management strategies.
Detailed description
Upper gastrointestinal bleeding (UGIB) is a critical medical situation that arises when there is bleeding proximal to the ligament of Treitz \[1\]. This condition is a leading cause of morbidity and mortality, with death rates ranging from 5-14% and increasing to over 40% in patients with liver disease\[2\] Symptoms of UGIB may include anemia, hematemesis, melena, or hematochezia \[3\].
Neoplasms, arteriovenous malformations, esophageal varices, gastric ulcers, gastric erosions, duodenal ulcers, reflux esophagitis, Mallory-Weiss tears, and fundal varices are causes of UGIB \[4\].
Current strategies for managing UGIB emphasize early recognition and intervention. Endoscopy is the primary diagnostic and therapeutic modality, allowing for direct visualization of the gastrointestinal tract and enabling interventions such as cauterization, clipping, or band ligation to control bleeding \[5\]. Recent advancements in endoscopic techniques have improved outcomes by facilitating earlier detection and treatment of UGIB episodes. For instance, the use of hemostatic powders and over-the-scope clips has shown promise in managing refractory cases\[6,7\].
Endoscopic therapies may have resulted in earlier detection and treatment of UGIB, which could have led to a reduction in the incidence and severity of the condition. Upper GI endoscopy is considered the primary modality for identifying the underlying etiology and administering appropriate therapeutic measures to the patient present with upper GIT bleeding by ligation ,clips, electrocoagulation or by taking biopsies that help in diagnosis. The rationale for this research stems from the need to enhance understanding of UGIB's underlying causes and improve patient outcomes through timely endoscopic intervention. By identifying specific etiologies through upper endoscopy\[8,9\].
Interventions
- Device endoscope
findings in upper GIT Endoscopy
Primary outcome measures
- Endoscopic Findings in patients with upper GIT Bleeding [Time frame: one year]
Eligibility criteria
Inclusion criteria
- Adult patients present with upper GIT bleeding of both gender older than 18 years old
Exclusion criteria
- 1- Patients younger than 18 2- Pregnant women 3- patients with end stage disease that not fit for endoscopic intervention
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Elsebaey MA, Elashry H, Elbedewy TA, Elhadidy AA, Esheba NE, Ezat S, Negm MS, Abo-Amer YE, Abgeegy ME, Elsergany HF, Mansour L, Abd-Elsalam S. Predictors of in-hospital mortality in a cohort of elderly Egyptian patients with acute upper gastrointestinal bleeding. Medicine (Baltimore). 2018 Apr;97(16):e0403. doi: 10.1097/MD.0000000000010403. PMID 29668596
Identifiers
NCT: NCT06886880 · Endoscope in GIT bleeding