Mi-RNA and COVID-19
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: mi-RNA analysis.
- Who it may be relevant to
- Registry conditions: COVID-19. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Circulating Mi-RNA Associated With Disease Severity and Outcome in COVID-19 Patients
Overview
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), induces a spectrum of clinical conditions ranging from asymptomatic infection to life threatening severe disease, characterized by respiratory failure, shock and multi-organ dysfunction requiring admission in the intensive care unit (ICU). The aim of the present study is to analyze miRNAs associated with SARS-CoV-2 infection, disease severity and mortality.
Interventions
- Diagnostic test mi-RNA analysis
To identify biomarkers that could predict the risk of a worsened COVID-19 disease progression.
Primary outcome measures
- Severity of Covid-19 [Time frame: Through study completion, an average of 1 year]
Eligibility criteria
Inclusion criteria
- 18 years
- diagnosis of SARS-CoV-2 infection confirmed by molecular testing on nasopharyngeal swabs
Exclusion criteria
- pregnant women
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-control
Study locations
Italy · 1 center
- Fondazione Policlinico Universitario A. Gemelli IRCCS — Roma
Identifiers
NCT: NCT06881160 · 3155