Ultrasound Acute Chest Syndrome Sickle Cell Disease
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Point of Care Ultrasound.
- Who it may be relevant to
- Registry conditions: Acute Chest Syndrome, Sickle Cell Disease. Basic parameters: up to 25 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Use of Point-of-Care Ultrasound (POCUS) for the Diagnosis of Acute Chest Syndrome in Patients With Sickle Cell Disease
Overview
Feasibility and reliability of ultrasound in the inpatient hematology setting.
Detailed description
Acute chest syndrome (ACS) is a complication of sickle cell disease where individuals have symptoms of fever, low oxygen levels or difficulty breathing in the setting of a new lung finding on chest x-ray. Chest x-ray is a useful tool to identify it but has some side effects. The investigators think ultrasound will be an equally feasible, reliable tool and minimize some of the side effects associated with chest x-ray. Ultrasound is a non-invasive was to obtain an image that does not require radiation.
Interventions
- Device Point of Care Ultrasound
Point of Care Ultrasound during hospitalization
Primary outcome measures
- Participation rate [Time frame: Up to 5 days]
- Retention rate [Time frame: Up to 5 days]
- Duration of exam [Time frame: Up to 5 days]
- Acceptability of POCUS by the medical team (physicians and nursing) [Time frame: Up to 5 days]
Secondary outcome measures (1)
- Reliability of point of care ultrasound (POCUS) compared to standard of care (Chest X-ray) [Time frame: Up to 5 days]
Eligibility criteria
Inclusion criteria
- Age: 0-25 years old
- Diagnosis: Patients with a documented diagnosis of sickle cell disease (any genotype)
- Disposition: Hospitalized for a SCD-related complication (e.g. VOC)
Exclusion criteria
- Patient is considered hemodynamically unstable to undergo consent and study procedures
- Already has diagnosis of ACS prior to admission to inpatient unit
- POCUS operator not available
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Diagnostic
Study locations
United States · 1 center
- Indiana University — Indianapolis
Identifiers
NCT: NCT06880679 · PHO-IIR-POCUS