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Not yet recruiting NCT06879483

Thoraco-laparoscopic Partial Esophagogastrectomy for Management of Esophageal Cancer

No phase Interventional Esophageal Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Thoraco-laparoscopic partial esophagogastrectomy.
Who it may be relevant to
Registry conditions: Esophageal Cancer. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Early and Intermediate Term Outcomes of Thoraco-laparoscopic Partial Esophagogastrectomy for Management of Esophageal Cancer

Overview

Thoraco-laparoscopic partial esophagogastrectomy has emerged as a promising minimally invasive alternative, combining thoracoscopy and laparoscopy to reduce the trauma associated with open surgery.Early and intermediate-term outcomes provide critical information on both the oncological efficacy and functional benefits of the procedure. By examining recurrence rates within the first 12-24 months, this study will provide valuable insights into the oncological robustness of this approach compared to more invasive approaches.

Interventions

  • Procedure Thoraco-laparoscopic partial esophagogastrectomy
    1. Laparoscopic Phase: * The stomach is mobilized, and a part of it is resected to include the lower esophageal segment. * Left gastric nodes, the splenic and common hepatic nodes are dissected. * A gastric tube is created using endoscopic staplers for esophageal reconstruction and fixed to the proximal gastrectomy specimen using sutures 2. Thoracoscopic Phase: * The patient is positioned in prone position * Three small incisions are made in the thorax * Further esophageal mo

Primary outcome measures

  • Immediate Postoperative complications [Time frame: first month post operative]
  • Dysphagia [Time frame: Collected at base line preoperative,one month, and 12 months post-surgery.]
  • resection margin status [Time frame: 2 weeks postoperative]
  • lymph node yield. [Time frame: first month post operative]
  • regurgitation [Time frame: Collected at one month, and 12 months post-surgery.]
Secondary outcome measures (3)
  • recurrence rate [Time frame: first year post operative]
  • body mass index [Time frame: Collected at base line preoperative,one month, and 12 months post-surgery.]
  • serum albumin [Time frame: Collected at base line preoperative,one month, and 12 months post-surgery.]

Eligibility criteria

Inclusion criteria

  • Patients diagnosed with resectable esophageal cancer (stages I-III).
  • Suitable for thoraco-laparoscopic partial esophagogastrectomy.
  • Eastern Cooperative Oncology Group (ECOG) performance status 0-2.

Exclusion criteria

  • Presence of distant metastasis at diagnosis.
  • History of previous esophageal or gastric surgery.
  • Contraindications to laparoscopy or thoracoscopy.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Sohag Faculty of Medicine — Sohag

Identifiers

NCT: NCT06879483 · Soh-Med-25-2-5MD

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗