Low and Moderete Flow Anaesthesia on Haemodynamics
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Sevoflurane (Volatile Anesthetic), low- medium flow anesthetic machine.
- Who it may be relevant to
- Registry conditions: Hemodynamics Instability, Arrhythmias Cardiac, Cerebral Oxygenation. Basic parameters: 17 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Comparison of the Effects of Low and Medium Flow Anesthesia on Haemodynamics, Arrhytmia Risk and Cerebral Oxygenation in Laparoscopic Cholecystomy Cases
Overview
The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.
Detailed description
The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery. The primary objective was to evaluate the effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk; the secondary objective was to compare the total sevoflurane consumption in both methods.
Interventions
- Device Sevoflurane (Volatile Anesthetic)
Both groups will be given sevoflurane and one group will be given low current anesthesia and the other group will be given medium flow anesthesia. - Device low- medium flow anesthetic machine
The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery.
Primary outcome measures
- the effects of low-flow anesthesia on hemodynamic stability [Time frame: in 2 months]
Secondary outcome measures (1)
- the cerebral oxygenation [Time frame: in 2 months]
Eligibility criteria
Inclusion criteria
- being ASA1-2 status
- between the ages of 18-70
- who are planned for laparoscopic cholecystectomy
Exclusion criteria
- Patients who refuse to give informed consent
- Pregnant and breastfeeding patients
- Morbidly obese patients (Body mass index over 40)
- Patients with uncontrolled diabetes mellitus, with serious cardiovascular, pulmonary, renal, hepatic disease, obstructive sleep apnea, with electrolyte imbalance- Those with a history of alcohol or drug abuse, with perioperative hemodynamic instability
- Patients using drugs known to prolong myocardial repolarization
- inability to increase SPO2 above 95 despite necessary intervention
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Quadruple blind
- Primary purpose
- Screening
Study locations
Turkey (Türkiye) · 1 center
- Umraniye Education and research hospital — Istanbul
Identifiers
NCT: NCT06871371 · LFATUGCE