Cooperative Extension and Cancer Survivorship
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: SUCCESS.
- Who it may be relevant to
- Registry conditions: Cancer Survivorship. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Cooperative Extension and Cancer Survivorship: Supportive Care Via Cooperative Extension Services (SUCCESS)
Overview
The goal of this clinical trial is to learn if a cancer survivor program, delivered via Cooperative Extension, is feasible and if it can improve health outcomes in cancer survivors who are post-active treatment. Aim 1: Evaluate the feasibility and acceptability of SUCCESS. Hypothesis 1: SUCCESS will be feasible and acceptable as evidenced by delivery of the intervention among Educators (implementation), including in agreement with the curriculum in Phase 1 (fidelity) with \>85% attendance (demand) among participants with \>80% rating the intervention as acceptable or highly acceptable on 5-point Likert-type scale (acceptability). Aim 2: Determine the preliminary efficacy of SUCCESS for improving HRQOL (primary outcome) and other psychosocial and health-related endpoints (e.g., financial toxicity) (secondary outcomes). Hypothesis 2: Compared to matched controls, adults LWBC who complete SUCCESS will have significant improvements in HRQOL per the PROMIS Global Health v1.2 at follow-up (i.e., after 6 weeks). Aim 3: Examine changes in conserved transcriptional response to adversity (CTRA) gene expression in a subset of interventions participants at follow-up. Hypothesis 3: Adults LWBC who complete SUCCESS will experience significant CTRA down-regulation. This is a single arm trial and there is no comparison group. Participants will be asked to do survey- and Zoom-based data collection before and after completing the 6-week program.
Interventions
- Behavioral SUCCESS
6 group-based sessions with 25 minutes of didactic content, 25 minutes of facilitated support group, and 10 minutes of group physical activity
Primary outcome measures
- Delivery of sessions [Time frame: Once per week for six weeks]
- Fidelity to SUCCESS protocol [Time frame: Once per week for six weeks]
- Participant attendance [Time frame: Once per week for six weeks]
- Acceptability of SUCCESS [Time frame: Measured after SUCCESS (week 7-8 of the clinical trial)]
Secondary outcome measures (12)
- Diet quality [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Physical function [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Depressive symptoms [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Anxiety symptoms [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Loneliness [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Social isolation [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Financial Toxicity [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Health-related quality of life [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Food insecurity [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Basic psychological needs [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Self-reported pain [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
- Conserved Transcriptional Response to Adversity (CTRA) gene expression [Time frame: Baseline (week 1) and post-SUCCESS (week 7-8)]
Eligibility criteria
Inclusion criteria
- Previous adult-diagnosed cancer
- Post active cancer treatment
- No current active treatment, hormonal therapy permitted
- Ability to get to group sessions
- In Oklahoma
Exclusion criteria
- Current palliative or hospice care
- Surgical or medical history that precludes participation
- Positive screen on the Physical Activity Readiness Questionnaire+ (PAR-Q+) without a doctor's note approving study participation
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Supportive care
Study locations
United States · 1 center
- University of Oklahoma — Tulsa
Publications
- Pitasi O, Hildebrand D, Liebe R, Joyce J, Nagykaldi Z, Robertson MC, Braun A. Hiding in plain sight: Cooperative Extension as an underutilized approach to improving cancer survivorship outcomes in underserved populations. J Cancer Surviv. 2026 Apr;20(2):792-803. doi: 10.1007/s11764-024-01687-z. Epub 2024 Oct 10. PMID 39388009
Identifiers
NCT: NCT06869512 · 17371