Randomized Controlled Trial of Remote Symptoms Monitoring With Resilience PRO Compared to Care As Usual Only
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Resilience PRO.
- Who it may be relevant to
- Registry conditions: Cancer. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France, Germany
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Digital Monitoring With Patient-Reported Outcomes in Cancer Care: A Randomized Controlled Trial RC - 102 (Resilience Care - 102)
Overview
The goal of this clinical trial is to learn if Resilience PRO, a digital solution performing remote symptoms monitoring, can improve the quality of life of patients with a diagnosis of cancer receiving systemic anticancer treatment. The main question it aims to answer is: \- Do patients with a diagnosis of cancer receiving systemic anticancer therapy and using Resilience PRO have an improved quality of life? Researchers will compare patients using Resilience PRO plus care as usual to patients receiving care as usual only. Participants in the intervention arm will use Resilience PRO, a mobile phone application regularly asking participants about their symptoms. For clinically important symptoms, an alert is sent to the care team that can incorporate that information to timely adjust the care of the participants. Participants both in the control arm and in the intervention arm will further receive care as usual.
Detailed description
Resilience PRO is a digital medical device (dMD CE marked, class IIa) that enables the remote monitoring of patients diagnosed with cancer receiving anticancer systemic therapy. Resilience PRO has been positively evaluated by the French health authorities (HAS, Haute Autorité de Santé) and is registered on the French LATM list (Liste des Activités de Télésurveillance Médicale).
Resilience PRO is a software medical device prescribed by cancer treating physicians to collect electronic patient-reported outcomes (ePRO). The Resilience PRO workflow comprises the following steps:
* Step 1. Collection of ePRO * Step 2. Intelligent analysis and alerts * Step 3. Adapted care
Interventions
- Device Resilience PRO
The patient will use Resilience PRO remote symptoms monitoring.
Primary outcome measures
- Health-Related quality of life [Time frame: 3 months]
Secondary outcome measures (2)
- Health-economic evaluation [Time frame: 12 months]
- Overall survival [Time frame: 36 months]
Eligibility criteria
Inclusion criteria
- Age: Adults ≥ 18 years.
- Informed Consent: Patient giving signed informed consent to participate in the RC - 102 clinical study.
- Diagnosis: Patients with cancer at any stage.
- Systemic Treatment
- Remote Monitoring Eligibility: Access to a smartphone
- Language: Ability to understand and communicate in the language(s) in which the trial is conducted.
Exclusion criteria
- Age: Patients under 18 years of age.
- Life Expectancy: Patients with a life expectancy of less than 6 months as estimated by the treating physician.
- Concurrent remote monitoring
- HSCT or CAR-T Therapy
- Cognitive Impairment
- Pregnancy or breastfeeding
- Subject under administrative or judicial control
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Supportive care
Study locations
France · 26 centers
- Hôpital Privé de Provence — Aix-en-Provence
- Centre Hospitalier du Pays d'Aix - Centre Hospitalier Intercommunal Aix-Pertuis — Aix-en-Provence
- Centre Hospitalier Henri Mondor-Aurillac — Aurillac
- Centre Hospitalier de la Côte Basque — Bayonne
- Centre Hospitalier Universitaire de Caen Normandie — Caen
- Centre Hospitalier Universitaire de Clermont-Ferrand — Clermont-Ferrand
- Centre Hospitalier Universitaire Grenoble - Alpes — La Tronche
- GHICL Hôpital Saint Vincent de Paul — Lille
- … and 18 more centers
Germany · 10 centers
- University Hospital Augsburg - UKA — Augsburg
- Helios Klinikum Bad Saarow — Bad Saarow
- Katholisches Klinikum Bochum UK St. Josef - Hospital — Bochum
- UK Hamburg- Eppendorf (UKE) — Hamburg
- Medizinische Hochschule Hannover — Hanover
- MVZ Aschaffenburg-Alzenau — Hösbach
- Universitätsklinikum Schleswig-Holstein (UKSH), Campus Kiel — Kiel
- Universitätsklinikum Schleswig-Holstein (UKSH), Campus Lübeck — Lübeck
- … and 2 more centers
Identifiers
NCT: NCT06867705 · RC-102 · 2024-A01584-43 (ID RCB) · N° Eudamed: CIV-25-01-050834