The Beijing Longitudinal Disability Survey in Community Elderly
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Ageing, Disability, Cognitive Impairment, Frailty. Basic parameters: from 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The goal of this observational study is to establish the prospective cohort of the Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE) to explore the high-risk factors and preventive interventions for disability and cognitive impairment among community-dwelling adults aged 65 years and over. The main question it aims to answer is: * What are the high-risk factors able to predict the incidence and advance of disability and cognitive impairment in community-dwelling adults aged 65 years and over? * What are the categories of function and cognitive performance trajectory in community-dwelling adults aged 65 years and over?
Detailed description
BLINDSCE is a community-based prospective cohort study that includes individuals aged 65 and over from urban and rural areas in Beijing. Participants will provide detailed demographic information and undergo multifactorial questionnaires, disability measurements, cognitive assessments, other disability-related outcomes, and clinical biochemical measures. The study has started recruitment and enrollment in 2023 and will follow-up once every 1-2 year. This work consists of three steps as follows. First, by collecting baseline and follow-up data of participants, we plan to establish a community-dwelling elderly database in Beijing. Second, high-risk factors can be pre-screening based on this cross-sectional analysis. Third, longitudinal data was used to develop the prediction model and trajectory analysis for disability and cognitive impairment.
Primary outcome measures
- Disability from the individual's perspective [Time frame: An average of 1 to 2 years]
- Disability from the medical's perspective [Time frame: An average of 1 to 2 years]
- Disability from the medical's perspective [Time frame: An average of 1 to 2 years]
Secondary outcome measures (12)
- Cognitive impairment [Time frame: An average of 1 to 2 years]
- Cognitive impairment [Time frame: An average of 1 to 2 years]
- Subjective cognitive decline [Time frame: An average of 1 to 2 years]
- Intrinsic capacity [Time frame: An average of 1 to 2 years]
- Intrinsic capacity [Time frame: An average of 1 to 2 years]
- Frailty [Time frame: An average of 1 to 2 years]
- Hospitalization [Time frame: An average of 1 to 2 years]
- Death [Time frame: An average of 1 to 2 years]
- Appendicular skeletal muscle mass [Time frame: An average of 1 to 2 years]
- Muscle strength [Time frame: An average of 1 to 2 years]
- Physical performance [Time frame: An average of 1 to 2 years]
- Sarcopenia [Time frame: An average of 1 to 2 years]
Eligibility criteria
Inclusion criteria
- Community-dwelling adults aged 65 years or older who reside in Beijing.
- Participants who sign an institutionally approved informed consent.
Exclusion criteria
- Participants with severe mental disorders and serious medical conditions preventing study investigation
- Participants undergoing long-term professional treatment for physical function and cognitive functioning, such as hospitalization or rehabilitation.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Xuanwu Hospital, Capital Medical University — Beijing
Publications
- Cheng S, Du X, Hou C, Liu H, Lei S, Wu Y, Yue X, Guo Y. Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE): protocol for a community-based prospective longitudinal cohort study about disability prediction model. BMJ Open. 2025 May 15;15(5):e091955. doi: 10.1136/bmjopen-2024-091955. PMID 40379348
Identifiers
NCT: NCT06863727 · No.[2023]129 · 2024-2G-20112