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Recruiting NCT06863051

Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant

No phase Interventional Immediate Implant Placement

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Immediate Implant Placement and Alb-PRF, Immediate Implant Placement and L-PRF.
Who it may be relevant to
Registry conditions: Immediate Implant Placement. Basic parameters: 18 years — 45 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Clinical and Radiographic Evaluation of Xenograft With Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant Placement in Mandibular Molar Extraction Sites: Randomized Clinical Trial.

Overview

The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.

Detailed description

The objective of this study will be to compare between xenograft with Alb-PRF gel and xenograft with L-PRF ( L-PRF Block ) in the aspects of :

* Peri-implant vertical defect depth. * Crestal bone level. * Bucco-lingual bone width. * Keratinized tissue width

Interventions

  • Procedure Immediate Implant Placement and Alb-PRF
    Immediate Implant Placement in lower molar region, Grafted with Xenograft and Albumin PRF Gel
  • Procedure Immediate Implant Placement and L-PRF
    Immediate Implant Placement in lower molar region, Grafted with Xenograft and L-PRF

Primary outcome measures

  • Vertical peri-implant bone level [Time frame: Immediate Post-Operative and 6 months after surgery]
  • Keratinized tissue Width [Time frame: Immediate Post-Operative and 6 months after surgery]
  • Crestal bone level [Time frame: Immediate Post-Operative and 6 months after surgery]
Secondary outcome measures (2)
  • Implant Stability [Time frame: Immediate Post-Operative and 6 months after surgery]
  • Bucco-lingual bone width [Time frame: Immediate Post-Operative and 6 months after surgery]

Eligibility criteria

  • Inclusion criteria
  • The presence of non-restorable mandibular molar.
  • Patient 18-45 years old
  • Intact buccal and lingual walls
  • Good oral hygiene.
  • Prescence of sufficient restorative space.
  • Jumping gap more than 2 mm.
  • Exclusion criteria
  • Proximity of anatomical structures
  • Acute localized infection (suppuration at the surgical field)
  • Patients on chemotherapy or radiotherapy.
  • Patients who have systemic disorders (diseases) {diabetes mellitus, autoimmune disease, …etc},
  • Pregnant patients.
  • Smoking and Alcohols.
  • Presence of periapical pathology affecting the neighboring teeth.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Kafrelsheikh University, Faculty of Dentistry — Kafr ash Shaykh

Identifiers

NCT: NCT06863051 · KFSIRB200-531

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗