Menu
Not yet recruiting NCT06857162

Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning

No phase Interventional This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes Maternal Hemodynamic Maternal Positioning During CS

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Positioninng during Cs.
Who it may be relevant to
Registry conditions: This Study Aims to Provide Evidence on Which Positioning Strategy Offers the Best Hemodynamic Outcomes, Maternal Hemodynamic, Maternal Positioning During CS. Basic parameters: 20 years — 40 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

Cesarean delivery is a common surgical procedure, and maintaining maternal hemodynamic stability during the procedure is crucial for both maternal and fetal outcomes . Hemodynamic instability, such as hypotension following spinal anesthesia, is a frequent complication and can lead to adverse maternal and neonatal outcomes. Traditionally, after spinal anesthesia, women are positioned supine, sometimes with a slight left lateral tilt to mitigate the risk of aortocaval compression . However, recent studies and clinical observations suggest that delayed supine positioning-keeping the patient in a sitting or semi-sitting position for a period following spinal anesthesiamay improve hemodynamic stability. These alternative positions may help to mitigate the abrupt drop in blood pressure commonly seen after spinal anesthesia by allowing for a more gradual redistribution of blood volume . Understanding the optimal positioning strategy could lead to improved clinical protocols that enhance maternal and fetal safety. By comparing immediate supine positioning with delayed supine positioning (in sitting and semi-sitting positions), this study aims to provide evidence on which positioning strategy offers the best hemodynamic outcomes.

Interventions

  • Behavioral Positioninng during Cs
    1. Group A (N=72): Immediate Supine Position (Control): Immediately after administering spinal anesthesia, participants will be placed in a supine position. To reduce the risk of aortocaval compression, a slight left lateral tilt (approximately 15 degrees) will be applied. This is the traditional positioning method and serves as the control group for comparison. 2. Group В (N=72): Sitting Position: After spinal anesthesia, participants will be positioned in a sitting position with the ac

Primary outcome measures

  • To compare the incidence and severity of hypotension in immediate supine, sitting, and semi-sitting positions during cesarean delivery. [Time frame: 9 Months]

Eligibility criteria

Inclusion criteria

  • Pregnant women scheduled for elective cesarean delivery.
  • Age between 18 and 40 years.
  • ASA (American Society of Anesthesiologists) physical status II.

Exclusion criteria

  • Emergency cesarean delivery.
  • Pre-existing cardiovascular disease.
  • Severe preeclampsia or eclampsia.
  • Multiple pregnancies.
  • Known fetal anomalies.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Prevention

Study locations

Egypt · 1 center
  • Aswan University Hospital — Aswān

Publications

  • Mohamady Eldemrdash A, Elabd Hassan I, Youssef Mohamed A, Ahmed Raslan HM. Post-spinal position and its impact on hemodynamic, block height, and comfort in caesarean delivery: A randomized assessor-blinded trial. Rev Esp Anestesiol Reanim (Engl Ed). 2026 Apr;73(4):502089. doi: 10.1016/j.redare.2026.502089. Epub 2026 Mar 21. PMID 41871806

Identifiers

NCT: NCT06857162 · 966/9/24

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗