Recruiting NCT06849375
Corneal Endothelial Assessment After Posterior Chamber Phakic Intraocular Lens Implantation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: phakic IOL implantation.
- Who it may be relevant to
- Registry conditions: Corneal Endothelial Cells. Basic parameters: 18 years — 35 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
our primary aim of the work to assess the effect of phakic IOL implantation on corneal endothelium. we also used the specular microscope to assess the corneal endothelium
Interventions
- Procedure phakic IOL implantation
specular microscopy examination to assess endothelial cells before and after phakic IOL implantation
Primary outcome measures
- corneal endothelial cells assessment [Time frame: 1 year]
Eligibility criteria
Inclusion criteria
- Our inclusion criteria include: adults 18-35 years of age, myopia ˃ 6 D , anterior chamber depth (ACD) 2.85 mm or greater , an endothelial cell count of ≥ 2000 cells/mm2 and stable refractive history within 0.5 diopter for 1 year.
Exclusion criteria
- anterior chamber depth from endothelium < 2.85 mm, previous or current systemic or eye disease , surgery or trauma, pregnancy and nursing.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Other
Study locations
Egypt · 1 center
- Sohag University Hospital — Sohag
Publications
- Reinstein DZ, MacGregor C, Archer TJ, Gupta R, Potter JG. A review of posterior chamber phakic intraocular lenses. Curr Opin Ophthalmol. 2024 Mar 1;35(2):138-146. doi: 10.1097/ICU.0000000000001018. Epub 2023 Dec 6. PMID 38059758
- Taneri S, Dick HB. Initial clinical outcomes of two different phakic posterior chamber IOLs for the correction of myopia and myopic astigmatism. Graefes Arch Clin Exp Ophthalmol. 2022 May;260(5):1763-1772. doi: 10.1007/s00417-021-05465-w. Epub 2021 Nov 6. PMID 34741659
- Chaurasia S, Vanathi M. Specular microscopy in clinical practice. Indian J Ophthalmol. 2021 Mar;69(3):517-524. doi: 10.4103/ijo.IJO_574_20. PMID 33595465
- Sridhar MS. Anatomy of cornea and ocular surface. Indian J Ophthalmol. 2018 Feb;66(2):190-194. doi: 10.4103/ijo.IJO_646_17. PMID 29380756
- DelMonte DW, Kim T. Anatomy and physiology of the cornea. J Cataract Refract Surg. 2011 Mar;37(3):588-98. doi: 10.1016/j.jcrs.2010.12.037. PMID 21333881
Identifiers
NCT: NCT06849375 · Soh-Med--25-1-11MS