Longitudinal Evaluation of a Fracture Liaison Service
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Osteoporosis. Basic parameters: from 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The major objective of this study is to evaluated osteoporosis prevalence, both on computed tomography (CT) and dual x ray absorptiometry (DXA) in patients included in a fracture liaison service (FLS). The secondary objectives are to evaluate the prevalence of antiosteoporotic treatments indication, of new fractures or mortality; to identify the risk factor for osteoporosis; the study the treatment's observance; to identify the screening threshold to diagnose osteoporosis on CT.
Primary outcome measures
- Osteoporosis prevalence on DXA and CT [Time frame: during the evaluation in the fracture liaison service FLS and evry year until 5 years]
Secondary outcome measures (8)
- prevalnce of treatment for osteoporosis [Time frame: during the evaluation in FLS and every year until 5 years]
- prevalence of new fractures at 1-3 and 5 years [Time frame: during the evaluation in FLS and at 1, 3 and 5 years]
- identification of osteoporosis risk factors [Time frame: at the inclusion in FLS]
- definition of the CT threshold for bone fragility in this population; [Time frame: at the inclusion in FLS]
- study of the correlation dual x ray absorptiometry and computed tomography bone fragility evaluation [Time frame: at the inclusion in FLS]
- study of the correlation between FRAX score and DXA [Time frame: at the inclusion in FLS]
- study of the correlation between FRAX score and Trabecular bone score TBS [Time frame: at the inclusion in FLS]
- study of the correlation between FRAX score and lean mass [Time frame: at the inclusion in FLS]
Eligibility criteria
Inclusion criteria
- age >= 50 years
- Bone fracture due to a fall
Exclusion criteria
- patient's opposition
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- CHRU Nancy — Vandœuvre-lès-Nancy
Identifiers
NCT: NCT06847776 · 2025PI010