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Not yet recruiting NCT06846151

Retinal Investigation Using Optos OCT Device

No phase Interventional AMD - Age-Related Macular Degeneration Retinitis Pigmentosa (RP) Diabetic Retinopathy Control Patients

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: retinal functional imaging.
Who it may be relevant to
Registry conditions: AMD - Age-Related Macular Degeneration, Retinitis Pigmentosa (RP), Diabetic Retinopathy, Control Patients. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Clinical Investigation of Optos OCT in Patients with Retinal Pathologies

Overview

Retinal investigation using OCT with control and diseased eyes

Interventions

  • Device retinal functional imaging
    this is a proof of concept study

Primary outcome measures

  • OCT physical response data [Time frame: 6 months from recruitment start]

Eligibility criteria

Inclusion criteria

  • Male or female participants 18 years of age or older who have full legal capacity to volunteer on the date the informed consent is signed.
  • Participants who understand the study and patient information sheet and can follow the instructions.
  • Participants who agree to participate in the study.
  • Control group where no retinal abnormalities were detected as part of the standard basic ophthalmic examination.
  • Participants with retinal disease in at least one eye including: Early dry age-related macular degeneration, late stage dry age-related macular degeneration specifically geographic atrophy, Wet age-related macular degeneration, Retinitis pigmentosa, Diabetic retinopathy and other macular atrophic diseases

Exclusion criteria

  • Inability to understand written and verbal English sufficiently to comprehend the study and provide informed consent
  • Ophthalmic disease other than condition under investigation.
  • Participants unable to tolerate ophthalmic imaging.
  • Cataract (unless deemed mild in the opinion of the investigator)
  • Participants with significant ocular media not sufficiently clear to obtain acceptable OCT images.
  • Diabetes (unless part of the diabetic eye disease group)
  • Binocular visual acuity worse than 6/18
  • Strabismus (squint)
  • Age related macular degeneration groups: polypoidal choroidal vasculopathy
  • Participants with photo sensitivity epilepsy, experience of seizures, or sensitivity to flickering light (based on self-report)
  • Pregnant

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Other

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT06846151 · OPT1105 · REC ref: 25/NS/0018 · IRAS Project ID: 338297

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗