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Recruiting NCT06843512

Identifying Changes in Food Behaviors Associated With Beginning GLP-1 Medication

— Observational Weight Loss Food Selection

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: GLP-1 Medication Initiation.
Who it may be relevant to
Registry conditions: Weight Loss, Food Selection. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Exploring the Influence of GLP-1 Medication on Food Attitudes and Selection in a Virtual Reality Buffet

Overview

In recent years, GLP-1 medications have become a widely employed approach by physicians to address weight concerns in patients and lead to weight loss. Little is known, however, about how these medications may alter an individual's attitude towards food, food reactivity, or the specific types and amounts of foods an individual will choose. The purpose of this study is to observe the changes an individual experiences in their relationship and reaction to food and in their food selection prior to or within the first two weeks of taking GLP-1 medication to after three months on the medication. The researchers of this study believe that an understanding of such changes can inform questions seeking to ensure maintenance of appropriate nutrient balance within individuals on weight loss medications.

Interventions

  • Other GLP-1 Medication Initiation
    One visit before starting GLP-1 medication and one visit 3 months after. No other changes administered between visits.

Primary outcome measures

  • Change from Baseline in Total Weight of Food Selected in the VR Buffet at 3 Months [Time frame: Baseline and 3 months]
  • Change from Baseline in Total Calories of Food Selected in the VR Buffet at 3 Months [Time frame: Baseline and 3 months]
  • Change from Baseline in Energy Density of Food Selected in the VR Buffet at 3 Months [Time frame: Baseline and 3 months]
  • Change from Baseline in Variety of Food Selected in the VR Buffet at 3 Months [Time frame: Baseline and 3 months]
Secondary outcome measures (6)
  • Change in Baseline Weight Watchers Food Noise Score at 3 Months [Time frame: Baseline and 3 months]
  • Change in Baseline 9-question External Food Cue Responsiveness Questionnaire Score at 3 Months [Time frame: Baseline and 3 months]
  • Change in Baseline Adult Eating Behavior Score at 3 Months [Time frame: Baseline and 3 months]
  • Change in Baseline Three-Factor Eating Questionnaire Score at 3 Months [Time frame: Baseline and 3 months]
  • Change in Baseline General Food Craving-Trait Scale Score at 3 Months [Time frame: Baseline and 3 months]
  • Change in Baseline Buffet Food Liking Scores at 3 Months [Time frame: Baseline and 3 months]

Eligibility criteria

Inclusion criteria

  • Adults (18+) with overweight or obesity (BMI >25 kg/m2)
  • Not currently taking an incretin-based medication at baseline
  • Recently (within two weeks) prescribed a GLP-1, can be included if they have a obesity-related co-occurring condition (diabetes, hypertension, cardiovascular disease, dyslipidemia)
  • Have had no prior diagnosis of cognitive or physical disability, dyslexia, or epilepsy.
  • Fluent in English

Exclusion criteria

  • Adults (18+) without overweight or obesity
  • <18 years of age at time of testing
  • Adults not taking a GLP-1 Medication
  • Adults taking a compound GLP-1
  • Adults on GLP-1 medication for longer than 2 weeks at baseline
  • Have had a prior diagnosis of cognitive or physical disability, dyslexia, or epilepsy.
  • Not fluent in English

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • Health, Ingestive Behavior, and Technology Laboratory of Pennsylvania State University — State College

Identifiers

NCT: NCT06843512 · STUDY00026642

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗