Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique.
- Who it may be relevant to
- Registry conditions: Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique. Basic parameters: 18 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Endoscopic ultrasound-guided liver biopsy (EUS-LB) can overcome many shortcomings of percutaneous liver biopsy and TJLB. Targeted and non-targeted liver biopsies can be done through this biopsy. It can be done in patients with international normalized ratio (INR) up to 2. It has less tissue fragmentation compared with TJLB. Needle entering the liver can be viewed in real-time (intrahepatic vessels and bile duct can be spared from injury) (Sharma et al., 2023). Both lobes of the liver can be accessed. It provides minimal patient discomfort. EUS-LB can access liver lesions that may not be safely accessible by routine US or computed tomography (tenBerge et al., 2002). It provides better results in obese individuals compared with percutaneous liver biopsy. It is safe in pregnant females requiring liver biopsy (Khare et al., 2024). Despite these advantages, EUS-LB is largely limited to tertiary care centers and its use is not yet widespread. This may be because, since its inception, numerous variations in needle shape, needle size, and, most notably, sampling techniques have been adopted. However, no consensus protocol for acquisition has been recognized, leading to poor procedural standardization and wide ranges of reported outcomes in sample quality and diagnostic yield. As such, there is a substantial need for a uniform technique that will safely maximize diagnostic performance with minimal needle passes (Khare et al., 2024).
Interventions
- Device Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique
Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique
Primary outcome measures
- Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique [Time frame: -Study period: Duration of the study will be 12 months after acceptance of The Ethical Committee Of The Medical Research. All patients will sign an informed written consent before starting the data collection with respect to patient's confidentiality.]
Eligibility criteria
Inclusion criteria
- The participants of the study were adults in need of liver biopsy for the evaluation of Altered liver function test
Exclusion criteria
- Using anti-platelets or anticoagulants within the last 5days
- Inability to provide informed consent
- Moderate-to-gross ascites
- Child C cirrhosis
- INR more than 2.01
- Platelet count less than 50,000/µL3
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Diagnostic
Study locations
Egypt · 1 center
- Sohag University — Sohag
Identifiers
NCT: NCT06833619 · Soh-Med-24-12---6MD