Study of the Anatomical and Functional Recovery and Quality of Life of Patients Undergoing Corneal Transplantation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cornea Transplant. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Prospective Observational Spontaneous Study of Anatomical, Functional and QoL Recovery of Patients Undergoing Corneal Transplantation
Overview
Evaluate the well-being of patients and clinicl outcomes of the cornea after transplantation
Detailed description
The study aims to evaluate patients affected by corneal diseases who will undergo corneal transplantation.
The evaluation will be carried out pre and post transplantation to evaluate the clinical outcome of the patients and the quality of life and functional anatomical recovery.
Primary outcome measures
- Anatomical recovery after corneal transplant [Time frame: postoperatively at 7 days, 30 days, 3 months, and 12 months.]
- Visual-functional recovery after corneal transplant [Time frame: postoperatively at 7 days, 30 days, 3 months, and 12 months.]
Secondary outcome measures (2)
- Patients's quality of life [Time frame: One week before surgery and at seven days, thirty days, three months, six months, one year, two years, three years, and four years after surgery.]
- Patients's quality of life [Time frame: One week before surgery and at seven days, thirty days, three months, six months, one year, two years, three years, and four years after surgery.]
Eligibility criteria
Inclusion criteria
- be eighteen years old
- diagnosis of corneal disease with prescription of surgical treatment of corneal transplantation
- sign the informed consent
Exclusion criteria
- no exclusion criteria
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Italy · 1 center
- IRCCS Azienda Ospedaliero-Universitaria di Bologna — Bologna
Publications
- Astolfi A, Potenza M, Ciavarella C, Moramarco A, Bonci P, Zaghi A, Foschi C, D'Eliseo LA, D'Eliseo D, Lazzarotto T, Fontana L, Versura P. Distinct Ocular Surface Microbial Profiles in Corneal Transplant Candidates. Cornea. 2026 Jun 12. doi: 10.1097/ICO.0000000000004088. Online ahead of print. PMID 42284092
Identifiers
NCT: NCT06830538 · OFTAFONTANA_OSS_TC