tDCS for Laryngeal Dystonia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Starstim system.
- Who it may be relevant to
- Registry conditions: Laryngeal Dystonia. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Network Targeted Transcranial Direct Current Stimulation (tDCS) as a Treatment for Laryngeal Dystonia (LD)
Overview
This project will apply transcranial direct current stimulation (tDCS) to multiple brain areas to evaluate the effects as a potential treatment for laryngeal dystonia (formerly spasmodic dysphonia).
Detailed description
Baseline neuroimaging data will be acquired from all participants via MRI, EEG. Each participant will be seen for multiple testing sessions over a five day period. LD participants will undergo the neuromodulation (HD-tDCS Stimulation) for twenty minutes while engaged in watching videos/movies or performing a word production task.
Interventions
- Device Starstim system
Transcranial direct current stimulation (tDCS)
Primary outcome measures
- Change in Cepstral peak prominence (CPP) [Time frame: daily on Day 1-Day 5]
- Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) [Time frame: daily on Day 1-Day 5]
Eligibility criteria
Inclusion criteria
- Participants must be clinically evaluated for the diagnosis of LD or have the proof of LD diagnosis. (Not applicable for control participants)
- No other known or history of speech, voice disorder other than LD.
- Provision of signed and dated informed consent form.
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Must not be pregnant.
Exclusion criteria
- All individuals who do not meet the above mentioned criteria are excluded from the study.
- Subjects with a history of epilepsy or depression or is claustrophobic.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
United States · 1 center
- Yale University — New Haven
Identifiers
NCT: NCT06830174 · 2000032414