Dietary Wild Blueberries and Joint Health
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Wild blueberry, Placebo.
- Who it may be relevant to
- Registry conditions: Gut -Microbiota, Inflammation Biomarkers, Pain Assessment, Joint Pain. Basic parameters: 40 years — 75 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effects of Dietary Wild Blueberries on Gut Health and Inflammation and Joint Pain
Overview
The goal of this proposed study is to examine the effects of dietary wild blueberries on gut microbiome, serum markers of inflammation, and joint function in adults. Each participant will consume 25g freeze-dried blueberries or matched placebo powder for 12 weeks, with a 2-week washout phase between.
Interventions
- Dietary supplement Wild blueberry
Freeze-dried wild blueberry powder 25g/day - Dietary supplement Placebo
Placebo powder matched for calories and no polyphenols
Primary outcome measures
- Serum biomarkers of joint function [Time frame: 12 weeks]
Secondary outcome measures (1)
- Gut microbiome [Time frame: 12 weeks]
Eligibility criteria
Inclusion criteria
- Adults with documented multi-joint/knee arthritis
Exclusion criteria
- inability to give informed consent
- pregnancy or lactation
- planned knee replacement surgery
- allergy or contraindication to berries
- recent trauma of the knee responsible of the symptomatic knee
- intra-articular injection in the target knee/hip in the last 3 months
- oral corticosteroid therapy ≥ 5 mg/day (prednisone equivalent) at baseline
- use of berry extracts in the last 3 months
- special diets
- cancer treatment
- bone diseases
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Crossover
- Masking
- Double blind
- Primary purpose
- Other
Study locations
United States · 1 center
- OMRF — Oklahoma City
Identifiers
NCT: NCT06828159 · OMRF WB01 · WBANA01