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Enrolling by invitation NCT06826976

Influence of Sensory Electrical Stimulation on Hand Functions in Chronic Stroke Patients

No phase Interventional Stroke Hand Functionality

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: sensory electrical stimulation, task specific training program.
Who it may be relevant to
Registry conditions: Stroke, Hand Functionality. Basic parameters: 40 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Overview

This study investigates the impact of sensory electrical nerve stimulation (SENS) on hand function in chronic stroke patients. Thirty participants were randomly divided into two groups: Study Group (A): Received SENS combined with task-specific training. Control Group (B): Received only task-specific training. Assessments conducted before and after the intervention included measurements of grip strength, pinch strength, wrist range of motion, and performance on the Action Research Arm Test (ARAT).

Detailed description

This study explores the effectiveness of sensory electrical nerve stimulation (SENS) in enhancing hand function among chronic stroke patients. Thirty participants were randomly divided into two groups:

Study Group (A): Received SENS combined with task-specific training.

Control Group (B): Received only task-specific training.

Assessment Methods:

Before and after the intervention, both groups underwent evaluations using:

Grip Dynamometer: To measure grip strength.

Pinch Dynamometer: To assess pinch strength.

Digital Goniometer: To determine wrist flexion and extension range of motion.

Action Research Arm Test (ARAT): To evaluate upper limb functional performance.

Interventions

  • Other sensory electrical stimulation
    peripheral sensory electrical stimulation on median, ulnar, and radial nerves of affected upper limb, simultaneously with Task Specific Training program which included four subtests of Action Research Arm Test scale.
  • Other task specific training program
    received task specific training program only. Patients were tested pre and post treatment by Grip dynamometer, Pinch dynamometer, Digital goniometer and Action Research Arm Test Scale (ARAT).

Primary outcome measures

  • Hand grip strength [Time frame: From enrollment to the end of treatment at end of 4th week]
  • wrist range of motion [Time frame: From enrollment to the end of treatment at end of 4th week]
  • pinch strength [Time frame: From enrollment to the end of treatment at end of 4th week]
  • hand functions [Time frame: From enrollment to the end of treatment at end of 4th week]

Eligibility criteria

Inclusion criteria

  • Patients who have experienced their first-ever ischemic stroke in the carotid system domain.
  • Age range: 40 to 65 years old.
  • Duration of illness: 30 to 180 days since stroke onset.
  • Spasticity of the affected hand muscles (wrist flexors, finger flexors, and finger adductors) must be grade 1+ or less according to the Modified Ashworth Scale.
  • Hand dysfunction severity ranges from mild to severe, defined by a score of ≤ 4 on the Medical Research Council Scale.

Exclusion criteria

  • Presence of a deformity in the paralytic upper limb before the stroke.
  • History of a lower motor neuron lesion in the impaired upper extremity (e.g., polyneuropathy) before the stroke.
  • Skin abrasions or ulcerations on the affected upper limb.
  • Unstable health conditions, including cardiac dysfunction, end-stage renal failure, unstable diabetes, or uncontrolled hypertension (>190/110).
  • Presence of a pacemaker or other implanted electrically sensitive devices.
  • Significant orthopedic conditions or chronic pain syndromes.
  • Chronic use of medications that may influence motor or sensory excitability (e.g., anti-epileptic or antipsychotic drugs).
  • Pregnancy.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Cairo University — Giza

Identifiers

NCT: NCT06826976 · P.T. REC/012/005208

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗