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Not yet recruiting NCT06826274

Cervical TsDCS on Stroke Patients

No phase Interventional Functional Recovery Motor Rehabilitation

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: tDCS.
Who it may be relevant to
Registry conditions: Functional Recovery, Motor Rehabilitation. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Clinical and Neurophysiological Evaluation of the Effects of Cervical TsDCS on Stroke Patients with Distal Upper Limb Strength Deficit

Overview

The present project aims to evaluate the facilitatory modulation of motor responses of the limb upper limb by tsDCS in patients with arm/hand hyposthenia after cerebral ischemia to verify the possible therapeutic benefits that this type of stimulation can induce in terms of of strength, dexterity and effectiveness in acts of daily living.

Interventions

  • Other tDCS
    Transcranial direct current stimulation

Primary outcome measures

  • improvement of paretic hand performance [Time frame: through study completion, an average of 1 year]
  • improvement of paretic hand performance [Time frame: through study completion, an average of 1 year]
  • improvement of paretic hand performance [Time frame: through study completion, an average of 1 year]
  • improvement of paretic hand performance [Time frame: through study completion, an average of 1 year]
  • improvement of paretic hand performance [Time frame: through study completion, an average of 1 year]

Eligibility criteria

Group Stroke:

Inclusion criteria

  • age over 18 years;
  • first ischemic/hemorrhagic stroke (within 30 days of onset);
  • mild-to-moderate stroke (NIHSS scale score<16).
  • residual function of the upper limb, assessed by the following scales: - MRC of the distal muscles of the upper limb: score between 2 and 4; - NHISS (items 5A and 5B): score between 1 and 3;
  • ability to give informed consent and understand instructions.

Exclusion criteria

  • severe spasticity (Ashworth Scale score > 2);
  • severe aphasia;
  • severe neglect;
  • history of disabling neurological disease;
  • history of epilepsy;
  • significant comorbidities;
  • contraindications to tsDCS.

Healthy Group:

Inclusion criteria

  • age over 18 years;
  • equalized in age with the patient group.

Exclusion criteria

  • history of stroke progress;
  • history of severe neurological disease.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Crossover
Masking
Single blind
Primary purpose
Treatment

Study locations

Italy · 1 center
  • IRCCS San Raffaele Roma — Rome

Identifiers

NCT: NCT06826274 · RP 23/06

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗