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Enrolling by invitation NCT06826209

Comparison of Upper Extremity Functional Performance in Hemophilic and Healthy Children

Observational Hemophilia Upper Extremity Strength Performance

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Hemophilia, Upper Extremity, Strength, Performance. Basic parameters: 7 years — 17 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Comparison of Upper Extremity Functional Performance, Muscle Strength, and Activities of Daily Living Levels in Children with Hemophilia and Healthy Children

Overview

The goal of this observational study is to evaluate the functional performance of the upper extremity joints (scapula, shoulder, elbow, and wrist) in haemophilic children and compare muscle strength and ADL limitations with healthy children.

Detailed description

This study aims to evaluate the upper extremity functional performance, muscle strength, and daily living activity levels of hemophilic children and compare them with healthy children. The goal is to determine the effects of hemophilia on these children and contribute to the development of appropriate rehabilitation strategies. Parameters include explosive strength, isometric muscle strength, wrist grip strength, and functional exercise capacity. Additionally, the ADL-Glittre pediatric version test and Hemophilia Joint Health Score (HJHS) will be used to assess joint health and GYA performance. Muscle strength is crucial for hemophilic children to perform daily activities, and the relationship between muscle strength and GYA levels will be investigated. The project aims to guide the development of physiotherapy and rehabilitation strategies for hemophilic children and contribute to the literature by filling existing gaps, ultimately creating an important reference for healthcare professionals and families.

Primary outcome measures

  • Hemophilia Joint Health Score [Time frame: Through study completion, an average of 1 year]
Secondary outcome measures (1)
  • Muscle Strength [Time frame: Through study completion, an average of 1 year]

Eligibility criteria

Inclusion criteria

  • Diagnosed with Hemophilia A or B
  • Receiving prophylaxis treatment (a routine treatment)
  • Negative for inhibitors at the time of enrollment

Exclusion criteria

  • Positive for inhibitors at the time of enrollment
  • Acute elbow bleeding
  • History of acute muscle bleeding
  • History of surgery in any upper extremity joints
  • Having undergone radionuclide synovectomy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Other

Study locations

Turkey (Türkiye) · 1 center
  • Hacettepe Universit — Ankara

Identifiers

NCT: NCT06826209 · FTREK24/103

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗