Uterine Doppler As StillbirthPredictor
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Intrauterine Fetal Death. Basic parameters: 18 years — 45 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The goal of this observational study is to define the predictive value of intrauterine fetal death for different longitudinal patterns of uterine artery Doppler indices (UtA-PI, UtA-RI and notch) from the second and third trimester of pregnancy in patients admitted with a diagnosis of intrauterine foetal death in the period January 2010-April 2020.
Detailed description
No changes in the obstetrical conduct of patients with MEFs are expected, since the data will be analysed retrospectively in patients in whom the event of intrauterine foetal death has already occurred. Patients will be treated according to normal clinical protocols.
The following information will be recorded for each patient
* Age * Body mass index (BMI) * Ethnicity * Parity * Method of pregnancy onset (spontaneous vs. medically assisted procreation) * Maternal pathologies (if any) * Any foetal pathologies * Ultrasound parameters in the second and third trimester of pregnancy
* Estimation of fetal weight * Umbilical artery Doppler (UA-PI) * Uterine artery Doppler (UtA-PI, UtA-RI and notch) * Gestational age of fetal endouterine death * Type of delivery * Newborn and placental weight * Histopathological findings of newborn and annexes (placenta and umbilical cord)
Primary outcome measures
- Evaluation of the association between uterine artery Doppler indexes (UtA-PI, UtA-RI and notch) and MEF [Time frame: From the 13th to the 24th weeks of pregnancy]
Eligibility criteria
Inclusion criteria
- Fetal endouterine death in single pregnancies with gestation period ≥ 24 weeks
- Obtaining informed consent form
Exclusion criteria
- Multiple pregnancies
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Italy · 1 center
- IRCCS Azienda Ospedaliero-Universitaria di Bologna — Bologna
Identifiers
NCT: NCT06825481 · StUtDop1.0