High-intensity Interval Training Combined with Muscle-strength Training in Older Women
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Exercise.
- Who it may be relevant to
- Registry conditions: Older Adult. Basic parameters: from 60 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United Kingdom
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Feasibility and Preliminary Efficacy of High-intensity Interval Training Combined with Muscle-strength Training in Older Women: Pilot Randomized Controlled Trial
Overview
Women generally live longer than men but often experience a faster muscle mass loss due to inactivity, which can lead to weakness and disability. Despite these risks, women, particularly older women, are less active than men. In England, less than one-third of women engage in sufficient aerobic activity, and less than 5% do enough muscle strength training. Common reasons for not exercising include lack of time and enjoyment. High-intensity interval training (HIIT) is an efficient and effective way to exercise that many women find more enjoyable than longer workouts. HIIT has been shown to be effective in older women, helping them improve their fitness with less time commitment. Because HIIT is time-efficient, it can be combined with muscle strength training without significantly increasing the duration of the exercise session, which may lead to even better fitness results. This study will assess how practical it is for older women to do HIIT and strength exercise combined training. It will also investigate whether this combined approach can improve overall fitness, muscle strength, aerobic fitness, and quality of life more than HIIT alone.
Interventions
- Behavioral Exercise
Participants will attend 30-min training sessions 3 times a week for 12 weeks. The intensity of HIIT will be at 80% HR@VT2 measured in the first week and will increase to 90% in the second week. By week 3, the intensity will reach HR@VT2.
Primary outcome measures
- Feasibility of high-intensity interval training combined with muscle strength training [Time frame: From recruitment to week-12]
Secondary outcome measures (5)
- functional capacity [Time frame: From baseline to week-12]
- muscle function [Time frame: From baseline to week-12]
- cardiorespiratory fitness [Time frame: From baseline to week-12]
- muscle mass [Time frame: From baseline to week-12]
- QoL [Time frame: From baseline to week-12]
Eligibility criteria
Inclusion criteria
- Females (biologically at birth)
- At least 60 years of age at the time of signing the informed consent
- Non-smoker, including electronic cigarettes
- Not participating in routine high-intensity aerobic or muscle strength exercise training (≥ 75 min/week of structured vigorous aerobic exercise, or 2 times /week of structured muscle strength training)
- Able to perform a cardiopulmonary exercise testing (CPET) to exhaustion
- willing to complete baseline and follow-up measures, and attend prescribed exercise sessions at the University of Nottingham
- willing and able to give informed consent for participation in the study
Exclusion criteria
- Diagnosed with cardiovascular disease, kidney disease, diabetes, obstructive pulmonary disease, or uncontrolled hypertension
- History or current neurological or psychiatric illness, or motor or cognitive restrictions
- Contraindications to symptom-limited cardiopulmonary exercise testing (CPET), including resting hypertension with systolic blood pressure >200 mmHg or diastolic blood pressure > 110 mmHg, uncorrected medical conditions, such as significant anemia, important electrolyte imbalance, and hyperthyroidism, mental impairment with limited ability to cooperate, physical disability that precludes safe and adequate testing.
- Having taken part in a research study in the last 3 months involving invasive procedures or an inconvenience allowance.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Prevention
Study locations
United Kingdom · 1 center
- David Greenfield Humnn Physiology Unit (DGHPU), University of Nottingham — Nottingham
Identifiers
NCT: NCT06825130 · FMHS 34-1124