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Recruiting NCT06815367

Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery

No phase Interventional Delayed Onset Muscle Soreness

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Pneumatic Compression, Blood Flow Restriction.
Who it may be relevant to
Registry conditions: Delayed Onset Muscle Soreness. Basic parameters: 18 years — 30 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Comparing the Effects of Pneumatic Compression and Blood Flow Restriction Therapy on Muscle Recovery

Overview

Both BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS). Blood flow restriction relies on applying pressurized cuffs to the most proximal portion of the limb. Another form of recovery often relied upon is pneumatic compression. The mechanism by which pneumatic compression works is similar to that of a massage, whereby the device progressively increases the pressure on a portion of the limb before releasing and moving further up the limb.The purpose of this study is determine whether BFR or pneumatic compression can be used to decreased DOMS which may indicate enhanced recovery.

Interventions

  • Device Pneumatic Compression
    Following downhill running protocol, participants will complete 20 minutes of pneumatic compression at 100 mmHg.
  • Device Blood Flow Restriction
    Following the downhill running protocol, participants will complete 4 rounds of treatment: 3 minutes at 100% resting limb occlusion pressure, 2 minutes of 0% resting limb occlusion pressure.

Primary outcome measures

  • Counter Movement Jump Height [Time frame: Immediately before and immediately after exercise, immediately after treatment, 24-hours post treatment.]
  • Maximal Voluntary Isometric Contraction [Time frame: Immediately before and immediately after exercise, immediately after treatment, 24-hours post treatment.]
  • Sedentary delayed onset muscle soreness [Time frame: Immediately before and immediately after exercise, immediately after treatment, 24-hours post treatment.]
  • Active delayed onset muscle soreness [Time frame: Using a visual analog scale, participants will be asked to rate their level of soreness while at rest.]

Eligibility criteria

Inclusion criteria

  • 18-30 years of age
  • Recreationally active population
  • Women should be on a form of hormonal contraception.
  • No current musculoskeletal injuries or pathologies
  • Must answer "yes" to all PAR-Q questions.

Exclusion criteria

  • Individuals that routinely train trail running
  • Discomfort when running
  • Deep vein thrombosis
  • Blood clots
  • Cancerous lesions
  • Sensory or mental impairment
  • Unstable fractures
  • Acute pulmonary edema
  • Acute thrombophlebitis
  • Acute congestive cardiac failure
  • Acute infections
  • Episodes of pulmonary embolism
  • Wounds, lesions, infection, or tumors
  • Bone fractures or dislocations
  • Increased venous and lymphatic return
  • Answers "no" to any of the PAR-Q screening questions

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

United States · 1 center
  • University of Southern California — Los Angeles

Identifiers

NCT: NCT06815367 · HS-23-00594

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗