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Not yet recruiting NCT06815016

Reflexology and Mulligan Mobilization for Knee Osteoarthritis

No phase Interventional Knee Osteoarthritis Knee Osteoarthritis (Knee OA)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Reflexology ,mulligan mobilization and conventional, reflexology and conventional, mulligan mobilization and conventional, Conventional treatment.
Who it may be relevant to
Registry conditions: Knee Osteoarthritis, Knee Osteoarthritis (Knee OA). Basic parameters: 40 years — 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Effect of Adding Reflexology to Mulligan Mobilization for Patient With Knee Osteoarthritis

Overview

to investigate the effect of adding Reflexlogy to mulligan mobilization and the conventional treatment for patients with Osteoarthritis knees

Detailed description

Knee osteoarthritis (OA), also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage. Treatment by reflexology stimulation increases blood flow to the associated organ or body part. On the other hand, the nerve impulse theory claims that reflexology stimulation boosts nervous connection to the conforming body parts. Regarding to the energy theory; organs and body parts are connected through electromagnetic fields and that these pathways are blocked in states of disease. Finally, lactic acid theory pointed that lactic acid accumulates on the soles of the feet in the form of crystals which promotes free circulation, so reduces regular flow .The effects of foot reflexology on improving physical complains of KOA. Therefore, this study was conducted to evaluate the effectiveness of reflexology foot massage on pain intensity and physical functional abilities among patients with Knee Osteoarthritis.

Mulligan's Mobilization with Movement (MWM) advocates therapist-applied accessory gliding force combined with active movement The goal of MWM is to achieve immediate pain relief possibly by regulation of the non-opioid pain sensory pathways and by correction of micro positional faults. These positional faults may result from changes in the shape of articular surfaces, cartilage thickness, fiber orientation in the capsule-ligamentous complex, and the direction of musculo-tendinous pull, causing altered mechanics in the osteoarthritic knees.

Interventions

  • Other Reflexology ,mulligan mobilization and conventional
    Reflexology is a systematic practice in which applying some pressure to any particular points on the feet and hands give impacts on the health of related parts of the body as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) Mulligan's Mobilization with Movement (MWM) apply accessory gliding force combined with active movement as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee fl
  • Other reflexology and conventional
    Reflexology as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.
  • Other mulligan mobilization and conventional
    Mulligan mobilization as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.
  • Other Conventional treatment
    Conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Primary outcome measures

  • visual analogue scale [Time frame: one month]
Secondary outcome measures (1)
  • The Knee Injury and Osteoarthritis Outcome Score (KOOS) [Time frame: one month]

Eligibility criteria

Inclusion criteria

  • Age greater than or equal to 40 years.
  • Body Mass Index ≤30 kg/m².
  • All participants have Calcium Deficiency
  • Osteoarthritis in mild and moderate stage not in the acute stage
  • The subjects were chosen from both genders

Exclusion criteria

  • Deep Vein Thrombosis
  • Fractures
  • Gangrena Patient
  • Osteopenic Patient
  • Lactating or pregnant women
  • Cancer
  • Neurological conditions.
  • Patients with injury including; (lesions, sprain, open wounds, foot ulcer and or burn of the lower extremities), hemorrhage, epilepsy, irregular heartbeat.
  • Vascular (Anticoagulant Therapy, Aortic Aneurysm)
  • Neurological Deficits (multilevel PIVD, Cervical Myelopathy)
  • Psychological Disorders.

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Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Cairo University — Cairo

Publications

  • Bakir E, Baglama SS. The Effect of Foot Reflexology and Knee Massage With Black Cumin Seed Oil on Knee Osteoarthritis Symptoms. Holist Nurs Pract. 2026 Jan-Feb 01;40(1):56-65. doi: 10.1097/HNP.0000000000000714. Epub 2025 Nov 11. PMID 39642267
  • Bhagat M, Neelapala YVR, Gangavelli R. Immediate effects of Mulligan's techniques on pain and functional mobility in individuals with knee osteoarthritis: A randomized control trial. Physiother Res Int. 2020 Jan;25(1):e1812. doi: 10.1002/pri.1812. Epub 2019 Sep 10. PMID 31502354

Identifiers

NCT: NCT06815016 · P.T.REC/012/005479

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗