Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Vastus lateralis nerve block, Lateral femoral cutaneous nerve block.
- Who it may be relevant to
- Registry conditions: Analgesia, Vastus Lateralis Nerve Block, Lateral Femoral Cutaneous Nerve Block, Knee Surgeries. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries: A Randomized Trial
Overview
This study aims to compare the analgesic efficacy and functional outcomes of blocking the nerve to the vastus lateralis (NVL) muscle versus the lateral femoral cutaneous nerve (LFCN).
Detailed description
Knee surgeries are associated with significant postoperative pain, which can impede early mobilization and prolong recovery. Recent advancements in ultrasound-guided regional anesthesia have enabled more targeted nerve blocks, such as the blockade of the nerve to the vastus lateralis (NVL) and the lateral femoral cutaneous nerve (LFCN)
Interventions
- Drug Vastus lateralis nerve block
Patients received vastus lateralis nerve block with 5 ml of bupivacaine 0.5%. - Drug Lateral femoral cutaneous nerve block
Patients received lateral femoral cutaneous nerve block with 5 ml of bupivacaine 0.5%.
Primary outcome measures
- Degree of pain [Time frame: 24 hours postoperatively]
Secondary outcome measures (6)
- Time to first request for analgesia [Time frame: 24 hours postoperatively]
- Total morphine consumption [Time frame: 24 hours postoperatively]
- Block performance time [Time frame: Intraoperatively]
- Degree of patient satisfaction [Time frame: 24 hours postoperatively]
- Length of hospital stay [Time frame: Till the discharge from hospital (Up to one week).]
- Incidence of adverse events [Time frame: 24 hours postoperatively]
Eligibility criteria
Inclusion criteria
- Age ≥ 18 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status from I to III.
- Underwent knee surgeries under spinal anesthesia.
Exclusion criteria
- Pregnancy.
- Coagulopathy.
- Neuromuscular disorders.
- Hematological disorders.
- Mental disorders.
- History of multiple traumas or anesthesia drug allergies.
- Local skin infection at the block site.
- Body mass index (BMI) greater than 40.
- Opioid analgesics or abusing opioids.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Kafrelsheikh University — Kafr ash Shaykh
Publications
- Arafa SK, Abdelwahed WM, Shama A, Elattar AM, Mustafa MM. Analgesic efficacy of blocking nerve to vastus lateralis muscle versus lateral femoral cutaneous nerve after knee surgeries: a randomized trial. BMC Anesthesiol. 2026 Mar 7;26(1):161. doi: 10.1186/s12871-026-03680-8. PMID 41794673
Identifiers
NCT: NCT06809842 · MKSU 50-1-4