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Enrolling by invitation NCT06805006

i-Stitch for Bilateral Sacrospinous Ligament Fixation (SSLF)

Observational Pelvic Organ Prolapse Genital Prolapse

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: SSLF.
Who it may be relevant to
Registry conditions: Pelvic Organ Prolapse, Genital Prolapse. Basic parameters: from 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Germany
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The purpose of the clinical investigation is to generate clinical data to substantiate the safety and performance of the i-Stitch device for bilateral sacrospinous ligament fixation (SSLF) in pelvic organ prolapse (POP) repair.

Detailed description

The i-Stitch instrument is a reusable instrument for attaching sutures to tissue with or without surgical mesh implants in urogynaecology. It is used together with the i-Stitch loading units. The use of i-Stitch for the fixation of surgical urogynaecological mesh implants (e.g. BSC Mesh, InGYNious) has already been proven in several studies.

The aim of the present retrospective study is to generate clinical data to show the safety and performance of the i-Stitch instrument in bilateral sacrospinous ligament fixation (SSLF) without the use of a surgical mesh.

Interventions

  • Device SSLF
    Bilateral sacrospinous ligament fixation with i-Stitch device

Primary outcome measures

  • Subjective outcome [Time frame: 12 months]
  • Subjective outcome [Time frame: 3 months]
Secondary outcome measures (3)
  • Quality of life (ICIQ-UI SF) [Time frame: 12 months]
  • Postoperative complications [Time frame: 12 months]
  • Anatomical outcome (POP-Q) [Time frame: 12 months]

Eligibility criteria

Inclusion criteria

  • Surgery for POP
  • SSLF with usage of i-Stitch device (\& i-Stitch Loading Units)
  • Concomitant procedures are allowed
  • Women minimum 18 years old
  • Written informed consent for surgery

Exclusion criteria

  • infection (active or latent)
  • allergies to the materials used
  • benign or malignant changes
  • anticoagulation disorders
  • autoimmune connective tissue disorders
  • any uterus pathologies

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Germany · 1 center
  • Isar Kliniken GmbH — Munich

Identifiers

NCT: NCT06805006 · PMCF-03-011

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗