Menu
Recruiting NCT06804525

LHC-CIDI-5 in Hong Kong

Observational Major Depressive Episode (MDE) Major Depressive Disorder (MDD) Persistent Depressive Disorder (PDD) Suicidal Ideation

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: CIDI-5, LHC-CIDI-5.
Who it may be relevant to
Registry conditions: Major Depressive Episode (MDE), Major Depressive Disorder (MDD), Persistent Depressive Disorder (PDD), Suicidal Ideation. Basic parameters: from 25 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Hong Kong
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Use of Life History Calendars to Enhance Measurement of Lifetime Experience With Mental Disorders in Hong Kong.

Overview

The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and lifetime) based on the diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and International Classification of Diseases 10th edition (ICD-10). However, retrospective measurements like the CIDI-5 are susceptible to recall bias, especially for the lifetime experience, which can hinder the reporting accuracy with mental disorders. To mitigate this issue, the life history calendar (LHC) was introduced as an aid to assist respondents in recalling the timing of life events, enhancing the ability of the CIDI-5 to measure the lifetime prevalence of mental disorders. The LHC is a grid structure with columns representing time units and rows representing life domains under study. In a study conducted in Nepal, combining the CIDI-5 with the LHC resulted in a significant increase in the detection of mental disorders compared to using the CIDI-5 alone. This approach did not lead to an increase in false positives after clinical validation. This experiment aims to adapt a Hong Kong version of the LHC based on the Nepalese model and evaluate the effectiveness of the LHC-assisted CIDI-5 (LHC-CIDI-5) compared to the CIDI-5 alone in assessing mental disorders.

Interventions

  • Diagnostic test CIDI-5
    The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and lifetime) based on the diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and International Classification of Diseases 10th edition (ICD-10) . Trained interviewers will administrate selected modules fr
  • Diagnostic test LHC-CIDI-5
    The interviewer will start by asking the respondent's age and significant personal experiences, which is expected to take 15 minutes. Remembering and recording the experiences provide cognitive engagement and information which can further serve as memory cues for respondents in the following screening of CIDI-5. Subsequently, the respondents will proceed to the screening section for CIDI-5 and will refer to the completed calendar from the LHC section when they are asked to report lifetime experi

Primary outcome measures

  • Depression [Time frame: Immediately following intervention or recruitment]
  • Persistent Depression [Time frame: Immediately following intervention or recruitment]
  • Self Harm [Time frame: Immediately following intervention or recruitment]
  • High Mood [Time frame: Immediately following intervention or recruitment]
  • Worry and Anxiety [Time frame: Immediately following intervention or recruitment]
  • Anger Attacks [Time frame: Immediately following intervention or recruitment]
  • Panic Attacks [Time frame: Immediately following intervention or recruitment]
  • Obsessions and Compulsions [Time frame: Immediately following intervention or recruitment]
  • Stressful Experiences [Time frame: Immediately following intervention or recruitment]
  • Tobacco, Alcohol, and Drugs [Time frame: Immediately following intervention or recruitment]

Eligibility criteria

Inclusion criteria

  • All household members aged 25 years old and over are randomly sampled from the Census and Statistics Department List of Quarters
  • Live in the address sampled from the Census and Statistics Department List of Quarters
  • Reside in Hong Kong for at least six months in the past year
  • Able to read and communicate in Chinese or English
  • Without linguistic or cognitive difficulties

Exclusion criteria

  • Domestic workers

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Ecologic or community

Study locations

Hong Kong · 1 center
  • The University of Hong Kong — Hong Kong

Publications

  • Amro I, Ali A, Hassan MHMO, Al Shawwaf M, Alhassan A, Al Bahari D, El Fakki H, Hijawi Z, Aly S, Amin A, Mohammed R, Nofal M, Abdelkader M, Salman S, Currie J, Alabdulla M, Sampson NA, First M, Kessler RC, Woodruff PW, Khaled SM. Design and field procedures for the clinical reappraisal of the Composite International Diagnostic Interview version 3.3 in Qatar's national mental health study. Int J Met PMID 36654500
  • Axinn WG, Chardoul S, Gatny H, Ghimire DJ, Smoller JW, Zhang Y, Scott KM. Using life history calendars to improve measurement of lifetime experience with mental disorders. Psychol Med. 2020 Feb;50(3):515-522. doi: 10.1017/S0033291719000394. Epub 2019 Mar 11. PMID 30854987

Identifiers

NCT: NCT06804525 · UW 24-771 · 2024-0089-004

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗