CanScan; Community-based Registry to Assess, Address and advaNce SCreening for cANcer Prevention and Management
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cancer Risk. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Early diagnosis of cancer allows for better treatment outcomes, higher survival rates, and lower costs of care. It is shown that cancer monitoring for cancer in at-risk populations is a key component in early diagnosis. The HMH Hennessey Institute for Cancer prevention and Applied Molecular Science (HICAP) is a newly founded institute, providing clinical services for cancer screening and risk assessment to the community, as well as research in cancer risk and prevention. The CanScan registry will prospectively collect data from participants in the form of questionnaires. The registry will also capture data that is collected as per non-research assessments, for participants who consent to participate. The registry will facilitate better understanding of cancer risk, screening, and diagnostics.
Primary outcome measures
- Rate of Pathogenic Germline Variants (PGV) [Time frame: 10 years from study initiation as defined based on the date the first patient was enrolled.]
Secondary outcome measures (4)
- Incidence of Cancer [Time frame: 10 years from study enrollment.]
- Genetic Risk Score (GRS) [Time frame: 10 years from study enrollment]
- Environmental and Lifestyle Factors [Time frame: 10 years from study enrollment]
- Impact of Early Detection and Prevention on Cancer Outcomes [Time frame: 10 years from study enrollment]
Eligibility criteria
- Adults ( 18 and older)
- Ability to provide own consent
- Must meet at least one of the below criteria, Indicating an increased risk for cancer, any of the following:
- Family or personal history suggests a familial/hereditary disorder known or suspected of predisposition to cancer.
- Personal factors associated with an increased risk for cancer include benign breast disease, polyps, tobacco use, etc.as defined by the investigator.
- Family members of participating individuals.
- Any participant in the HICAP program regardless of cancer risk
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Other
Study locations
United States · 1 center
- Hennessy Institute for Cancer Prevention and Applied Molecular Medicine — Totowa
Identifiers
NCT: NCT06804395 · Pro2024-0211