Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: physical test.
- Who it may be relevant to
- Registry conditions: Type 1 Diabetes. Basic parameters: 10 years — 16 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effets du Rythme Circadien Sur la régulation glycémique Lors d'Exercices modérés Continus et Intermittents Intenses Chez Des Adolescents Vivant Avec le diabète de Type 1
Overview
Interventional research with minimal risks and constraints on the effects of circadian rhythm on glycemic regulation during intense moderate, continuous and intermittent exercise in adolescents living with type 1 diabetes
Detailed description
Single-center, randomized, controlled study in adolescents living with type 1 diabetes. This study aims to evaluate the effect of exercise timing (morning vs. afternoon) and exercise type (continuous vs. intermittent) on blood glucose levels during and after exercise, as well as to assess the effect of exercise timing (morning vs. afternoon) and type of exercise (continuous vs. intermittent) on blood glucose during and after exercise
Interventions
- Other physical test
continuous and intermittent exercise on cycloergometer
Primary outcome measures
- Comparison of glycemic variation between the 4 conditions [Time frame: 1 year 10 months september 2026]
Eligibility criteria
Inclusion criteria
- Children and adolescents aged 10 to 16;
- Living with type 1 diabetes for at least 1 year with HbA1c less than or equal to 12%;
- Socially insured ;
- Having given their written consent to participate in the research, as well as that of their legal guardians;
- Willing to comply with all research procedures and duration.
Exclusion criteria
- Clinically significant microvascular complications: nephropathy (estimated glomerular filtration rate less than 40 ml/min), neuropathy or severe proliferative retinopathy as assessed by the investigator;
- Recent acute macrovascular event (< 3 months), e.g. acute coronary syndrome or cardiac surgery;
- Abnormal blood picture and/or anemia;
- Current pregnancy;
- Other serious medical condition likely to interfere with study participation or ability to complete exercise periods in the judgment of the investigator (e.g., orthopedic limitation);
- Inability to receive informed information;
- Inability to participate in the entire study;
- Lack of social security coverage;
- Refusal to sign the consent form.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Crossover
- Masking
- Open label
- Primary purpose
- Health services research
Study locations
France · 1 center
- Eurasport — Loos
Identifiers
NCT: NCT06803446 · D2024-05