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Recruiting NCT06801171

A Mixed Intervention to Improve Resilience for Patient With Neurocognitive Disorders

No phase Interventional Cognitive Disorder

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: cognitive stimulation, mixed intervention.
Who it may be relevant to
Registry conditions: Cognitive Disorder. Basic parameters: from 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Randomized Clinical Trial Testing a Mixed Intervention to Improve Resilience in People Aged Over 60 Years With Neurocognitive Disorders.

Overview

The study aims to test a program combining cognitive behavioral therapy techniques, positive psychology techniques, mindfulness meditation and yoga, in order to improve resilience in patient with minor cognitive disorder. This intervention will be compared to a control group, but also with a group testing another intervention (an intervention that does not improve resilience in the elderly, namely a "cognitive stimulation" intervention) in order to ensure that the effect potentially obtained is not due to the simple management of the participant. The duration of the intervention will be 3 months, with an evaluation directly before and after the intervention. In addition, in order to best evaluate the effectiveness of the interventions over time, two follow-up measurements will be proposed: a measurement one month after the intervention, then a final one three months after the intervention.

Interventions

  • Other cognitive stimulation
    12 sessions (one per week for 12 weeks) in group of cognitive stimulation
  • Other mixed intervention
    12 sessions (one per week for 12 weeks) in group of mixte stimulation (yoga, cognitive behavioral therapy, mindfullness meditation, positive psychology)

Primary outcome measures

  • Improvement of resilience of patients suffering from mild neurocognitive disorder (NCD) compared to a passive control group (without any intervention). [Time frame: Pre intervention]
  • Improvement of resilience of patients suffering from mild neurocognitive disorder (NCD) compared to a passive control group (without any intervention). [Time frame: Pre intervention]
  • Improvement of resilience of patients suffering from mild neurocognitive disorder (NCD) compared to a passive control group (without any intervention). [Time frame: Pre intervention]
Secondary outcome measures (3)
  • Persistence of improvement in resilience over time [Time frame: Through study completion, an average of 3 months]
  • Persistence of improvement in resilience over time [Time frame: Through study completion, an average of 3 months]
  • Persistence of improvement in resilience over time [Time frame: Through study completion, an average of 3 months]

Eligibility criteria

Inclusion criteria

  • Man or Woman aged > 60 years
  • Have a minor neurocognitive disorder according to the criteria of the DSM 5
  • Score of 145 or less on the Wagnild and Young Resilience Scale (RS) (Wagnild, 2009).
  • Subject able to read and write French;
  • Subject beneficiaries of a social security scheme;
  • Ability to understand and sign free and informed consent.

Exclusion criteria

  • Subject already practicing meditation and/or yoga and/or Tai Chi
  • Subject currently undergoing psychological therapy (whatever the approach)
  • Subject with a major hearing, visual or motor disability likely to interfere with the proposed interventions or the performance of assessments;
  • Presence and/or recent history (within the last 5 years prior to inclusion in the study) of major psychiatric disorders (e.g., schizophrenia, severe depression, addiction, bipolar disorders, psychotic disorders, risk of dissociation, panic attack, generalized anxiety disorder, etc.)
  • If taking psychotropic treatment, the dose must have been stable for 4 weeks
  • Vulnerable persons are defined in Articles L1121-5 to -8

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Supportive care

Study locations

France · 1 center
  • CHU de Nice — Nice

Identifiers

NCT: NCT06801171 · 24-AOI-02

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗