AI-Driven Prediction of Hospital-Acquired Infections With EHR
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: AI-Based Diagnostic and Prognostic Model.
- Who it may be relevant to
- Registry conditions: Hospital-acquired Infections. Basic parameters: 0 years — 90 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Predicting Hospital-Acquired Infections Using Electronic Health Records: An AI-Assisted Approach
Overview
This is a multi-center, clinical study designed to evaluate the application and effectiveness of an AI-assisted predictive model for identifying and diagnosing infection, leveraging multimodal health data.
Detailed description
Hospital-acquired infections (HAIs) are a significant cause of morbidity and mortality in healthcare settings. Early identification and prevention of HAIs are crucial for improving patient outcomes, reducing healthcare costs, and preventing the spread of infections. In clinical practice, healthcare providers often need to integrate a wide range of patient data, including medical history, laboratory test results, medication usage, surgical procedures, and clinical observations, to assess infection risks and prevent HAIs. As infection control and precision medicine become increasingly important, the challenge remains to predict and prevent infections, especially in patients with subtle or asymptomatic risk factors. Recent advancements in artificial intelligence and data analysis techniques have shown great promise in improving the accuracy and efficiency of infection prediction and prevention. This study aims to develop an AI-assisted decision-making system by integrating multimodal data from electronic health records, lab results, clinical observations, and patient demographics. The objective is to enhance the early identification of patients at risk for HAIs, streamline clinical workflows, and optimize infection control measures. Ultimately, this system seeks to reduce the incidence of hospital-acquired infections, improve patient safety, and enhance overall healthcare quality.
Interventions
- Diagnostic test AI-Based Diagnostic and Prognostic Model
This intervention involves an AI system that integrates multimodal data, including patient medical history, laboratory test results, clinical observations, and treatment data, to predict the risk of hospital-acquired infections (HAIs). The system uses deep learning algorithms to provide real-time, accurate predictions, enabling early identification of patients at risk for infections. By analyzing historical health data, the model aims to predict potential infection developments, improving early
Primary outcome measures
- Area Under the Curve (AUC) [Time frame: 1 year]
- F1 Score [Time frame: 1 year]
Secondary outcome measures (2)
- Sensitivity (True Positive Rate) [Time frame: 1 year]
- Specificity (True Negative Rate) [Time frame: 1 year]
Eligibility criteria
Inclusion criteria
- Patients with complete and accessible EHR data, including medical history, laboratory test results, treatment regimens, clinical observations, and infection history.
- Patients who have been admitted to the participating hospital or healthcare facility during the study period.
- All participants must provide informed consent to use their health data for research purposes.
Exclusion criteria
- Patients with incomplete or missing critical EHR data, such as lab results, medical history, or treatment details, which are necessary for infection prediction.
- Patients who have severe cognitive disorders, dementia, or conditions that prevent them from providing informed consent or participating in the study.
- Patients who have not been admitted to the hospital during the study period or who are receiving outpatient care only.
- Patients with terminal conditions where infection prediction may not be applicable to the clinical goals of the study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
China · 2 centers
- First Affiliated Hospital of Wenzhou Medical University — Wenzhou
- Second Affiliated Hospital of Wenzhou Medical University — Wenzhou
Identifiers
NCT: NCT06791382 · Hospital-Acquired Infections