Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Ultrasound guided needle knife dissection.
- Who it may be relevant to
- Registry conditions: Dupuytren Contracture. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Advancing Dupuytren's Contracture Treatment: a Clinical Prospective Study on Ultrasound-Guided Needle Knife Dissection
Overview
This study aims to evaluate the efficacy and safety of ultrasound-guided needle knife dissection in treating Dupuytren's contracture. The procedure is designed to improve hund function and minimize complications associated with the conventional surgical methods.
Detailed description
Dupuytren's contracture is a disease mainly characterized by the progressive fibrosis of the palmar fascia with subsequent hand deformity and dysfunction. The current study seeks to explore, through this minimally invasive technique, ultrasound-guided needle knife dissection regarding ROM and patient satisfaction. The procedure will be carried out under ultrasound guidance to ensure safety and completeness with the accuracy of precise dissection. Primary outcome measures will concern hand mobility, and secondary measures will evaluate patient self-reported satisfaction and any complications for the 6-month follow-up period.
Interventions
- Procedure Ultrasound guided needle knife dissection
This procedure involves a minimally invasive dissection of the fibrous cords in Dupuytren's Contracture using a needle knife guided by ultrasound imaging. Local anesthesia using 3-5 ml of 1% Lidocaine and 0.25% bupivacaine is administered for patient comfort. The technique aims to improve precision, minimize complications and reduce recurrence. Device: Sonosite M-Turbo Ultrasound Machine with Linear Probe HFL38x (6-13 MHz) is used for real-time imaging during the procedure.
Primary outcome measures
- Improvement in hand Function [Time frame: 6 months]
- Improvement in hand mobility [Time frame: 6 months]
Secondary outcome measures (2)
- Patient Satisfaction [Time frame: 6 months]
- Rate of procedure-related complications [Time frame: 6 months]
Eligibility criteria
Inclusion criteria
- Participants diagnosed with Dupuytren's Contracture.
- Willing to undergo ultrasound-guided needle knife dissection
Exclusion criteria
- Patients who have undergone previous surgery or needle apponeurotomy for Dupuytren's Contracture on the same hand.
- Active hand infections, open wounds, or dermatological conditions in the treatment area.
- Coagulopathy or use of anticoagulant that cannot be safely paused
- Neuromuscular disorders affecting hand function
- Pregnancy or breastfeeding
- Uncontrolled systemic illnesses, such as poorly managed diabetes or cardiovascular disease.
- Known hypersensitivity to local anesthetics.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Mansoura University Hospital — Al Mansurah
Identifiers
NCT: NCT06788847 · MansouraUH_DC-US_2025 · R.24.12.2966